| 產(chǎn)品編號(hào) | bs-8704R-BF594 |
| 英文名稱1 | Rabbit Anti-RBJ/BF594 Conjugated antibody |
| 中文名稱 | BF594標(biāo)記的RBJ蛋白抗體 |
| 別 名 | DJC27_HUMAN; DKFZp434N211; DnaJ (Hsp40) homolog, subfamily C, member 27; DnaJ homolog subfamily C member 27; DNAJC27; rab and DnaJ domain containing; Rab and DnaJ domain-containing protein; RABJS; Ras associated protein Rap1; RBJ. |
| 規(guī)格價(jià)格 | 100ul/2980元 購(gòu)買 大包裝/詢價(jià) |
| 說 明 書 | 100ul |
| 研究領(lǐng)域 | 腫瘤 細(xì)胞生物 信號(hào)轉(zhuǎn)導(dǎo) 結(jié)合蛋白 G蛋白信號(hào) |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | |
| 產(chǎn)品應(yīng)用 | ICC=1:50-200 IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 31kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human RBJ |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲(chǔ) 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
Function: GTPase which can activate the MEK/ERK pathway and induce cell transformation when overexpressed. May act as a nuclear scaffold for MAPK1, probably by association with MAPK1 nuclear export signal leading to enhanced ERK1/ERK2 signaling. Subunit: Interacts directly with MAPK1 (wild-type and kinase-deficient forms). Interacts directly (in GTP-bound form) with MAP2K1 (wild-type and kinase-deficient forms). Subcellular Location: Nucleus. Tissue Specificity: Overexpressed in gastrointestinal cancers; expression correlates with later tumor-node-metastasis stages of colorectal cancers. Similarity: Belongs to the small GTPase superfamily. Rab family. Contains 1 J domain. Database links: Entrez Gene: 402783 Chicken Entrez Gene: 51277 Human Entrez Gene: 217378 Mouse Entrez Gene: 402784 Zebrafish Omim: 613527 Human SwissProt: Q6IMM1 Chicken SwissProt: Q9NZQ0 Human SwissProt: Q8CFP6 Mouse SwissProt: Q6IMK3 Zebrafish Unigene: 434993 Human Unigene: 271656 Mouse Unigene: 22692 Rat Unigene: 92915 Zebrafish Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
