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Rabbit Anti-RBM15B/AP Conjugated antibody (bs-21289R-AP)
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說(shuō) 明 書(shū): 100ul  
100ul/2980.00元
大包裝/詢(xún)價(jià)
產(chǎn)品編號(hào) bs-21289R-AP
英文名稱(chēng) Rabbit Anti-RBM15B/AP Conjugated antibody
中文名稱(chēng) 堿性磷酸酶(AP)標(biāo)記的RNA結(jié)合蛋白15B抗體
別    名 1810017N16Rik; Chromosome 3p21.1 gene sequence; HUMAGCGB; huOTT3; One twenty two protein 3; One-twenty two protein 3; OTT3; Putative RNA binding protein 15B; Putative RNA-binding protein 15B; RB15B_HUMAN; RBM15B; RGD1305937; RNA binding motif protein 15B; RNA-binding motif protein 15B.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買(mǎi)        大包裝/詢(xún)價(jià)
說(shuō) 明 書(shū) 100ul  
研究領(lǐng)域 細(xì)胞生物  信號(hào)轉(zhuǎn)導(dǎo)  結(jié)合蛋白  表觀遺傳學(xué)  
抗體來(lái)源 Rabbit
克隆類(lèi)型 Polyclonal
交叉反應(yīng) Human,  (predicted: Mouse, Rat, Dog, Pig, Cow, Rabbit, Sheep, )
產(chǎn)品應(yīng)用 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 97kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human RBM15B
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
Members of the SPEN (Split-end) family of proteins, including RBM15B, have repressor function in several signaling pathways and may bind to RNA through interaction with spliceosome components (Hiriart et al., 2005 [PubMed 16129689]).[supplied by OMIM, Feb 2009]

Function:
May function in the regulation of alternative or illicit splicing.

Subcellular Location:
Nucleus > nucleoplasm. Colocalizes with BMLF1 in the nucleus. Localized in the nucleoplasm with a granular staining pattern and excluded from the nucleoli.

Tissue Specificity:
Ubiquitously expressed.

Similarity:
Belongs to the RRM Spen family.
Contains 3 RRM (RNA recognition motif) domains.
Contains 1 SPOC domain.

Database links:

Entrez Gene: 29890 Human

Entrez Gene: 109095 Mouse

Entrez Gene: 315988 Rat

Omim: 612602 Human

SwissProt: Q8NDT2 Human

SwissProt: Q6PHZ5 Mouse

Unigene: 118738 Human

Unigene: 431589 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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