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Rabbit Anti-LDHB/Cy7 Conjugated antibody (bs-20294R-Cy7)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-20294R-Cy7
英文名稱 Rabbit Anti-LDHB/Cy7 Conjugated antibody
中文名稱 Cy7標記的乳酸脫氫酶抗體
別    名 Lactate Dehydrogenase B; Renal Carcinoma Antigen NY-REN-46; LDH Heart Subunit; EC 1.1.1.27; LDH-B; LDH-H; Epididymis Secretory Protein Li 281; Lactate Dehydrogenase H Chain; HEL-S-281; EC 1.1.1; LDHBD; TRG-5; LDHB_HUMAN;   
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領(lǐng)域 細胞生物  新陳代謝  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse,  (predicted: Rat, Pig, Cow, Rabbit, )
產(chǎn)品應(yīng)用
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 37kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human LDHB
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
This gene encodes the B subunit of lactate dehydrogenase enzyme, which catalyzes the interconversion of pyruvate and lactate with concomitant interconversion of NADH and NAD+ in a post-glycolysis process. Recent studies have shown that two protein isoforms are produced from the same mRNA by use of alternative in-frame translation termination codons via a stop codon readthrough mechanism, and that these C-terminally distinct isoforms have different subcellular localization. Alternatively spliced transcript variants have also been found for this gene. Mutations in this gene are associated with lactate dehydrogenase B deficiency. Pseudogenes have been identified on chromosomes X, 5 and 13. [provided by RefSeq, Oct 2015]

Function:
This protein is involved in step 1 of the subpathway that synthesizes (S)-lactate from pyruvate.This subpathway is part of the pathway pyruvate fermentation to lactate, which is itself part of Fermentation.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes (S)-lactate from pyruvate, the pathway pyruvate fermentation to lactate and in Fermentation.

Subunit:
Homotetramer.

Subcellular Location:
Cytoplasm

Similarity:
Belongs to the LDH/MDH superfamily. LDH family.

Database links:

Entrez Gene: 3945 Human

Entrez Gene: 16832 Mouse

Entrez Gene: 24534 Rat

Omim: 150100 Human

SwissProt: P07195 Human

SwissProt: P16125 Mouse

SwissProt: P42123 Rat

Unigene: 446149 Human

Unigene: 9745 Mouse

Unigene: 1785 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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