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Mouse Anti-RAB18/BF488 Conjugated antibody (bsm-51333M-BF488)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bsm-51333M-BF488
英文名稱1 Mouse Anti-RAB18/BF488 Conjugated antibody
中文名稱 BF488標記的小鼠抗G蛋白家族RAB18蛋白單克隆抗體
別    名 RAB18; RAB18 member RAS oncogene family; RAB18 small GTPase; RAB18_HUMAN; RAB18LI1; Ras-related protein Rab-18.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領(lǐng)域 細胞生物  信號轉(zhuǎn)導  轉(zhuǎn)錄調(diào)節(jié)因子  G蛋白信號  
抗體來源 Mouse
克隆類型 Monoclonal
克 隆 號 3A8
交叉反應 (predicted: Human, Mouse, Rat, )
產(chǎn)品應用
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 23kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 Recombinant human RAB18 protein
亞    型 IgG1
純化方法 affinity purified by Protein G
儲 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
The protein encoded by this gene is a member of a family of Ras-related small GTPases that regulate membrane trafficking in organelles and transport vesicles. Knockdown studies is zebrafish suggest that this protein may have a role in eye and brain development. Mutations in this gene are associated with Warburg micro syndrome type 3. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012]

Function:
Plays a role in apical endocytosis/recycling. May be implicated in transport between the plasma membrane and early endosomes. Plays a key role in eye and brain development and neurodegeneration.

Subcellular Location:
Cell membrane; Lipid-anchor; Cytoplasmic side

Tissue Specificity:
Ubiquitous.

Similarity:
Belongs to the small GTPase superfamily. Rab family.

Database links:

Entrez Gene: 22931 Human

Entrez Gene: 19330 Mouse

Entrez Gene: 307039 Rat

Omim: 602207 Human

SwissProt: Q9NP72 Human

SwissProt: P35293 Mouse

SwissProt: Q5EB77 Rat

Unigene: 406799 Human

Unigene: 132802 Mouse

Unigene: 472772 Mouse

Unigene: 53248 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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