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Rabbit
Anti-PDE1C/HRP
Cat. Number:
bs-9969R-HRP
Quantity size:
100ul
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
Cyclic nucleotide phosphodiesterases (PDEs) catalyze hydrolysis of the cyclic nucleotides cAMP and cGMP to the corresponding nucleoside 5-prime-monophosphates. Mammalian PDEs have been classified into several families based on their biochemical properties. Members of the PDE1 family, such as PDE1C, are calmodulin (see MIM 114180)-dependent PDEs (CaM-PDEs) that are stimulated by a calcium-calmodulin complex (Repaske et al., 1992 [PubMed 1326532]).[supplied by OMIM, Oct 2009]
Also known as:
5''-cyclic nucleotide phosphodiesterase 1C;
Calcium/calmodulin dependent 3'5' cyclic nucleotide phosphodiesterase 1C;
Calcium/calmodulin-dependent 3'';
Cam PDE 1C;
Cam-PDE 1C;
hCam 3;
hCam-3;
HCAM3;
HSPDE1C1A;
Human 3'5' cyclic nucleotide Phosphodiesterase;
PDE 1C;
Pde1c;
PDE1C_HUMAN;
Phosphodiesterase 1C;
Phosphodiesterase 1C calmodulin dependent;
Phosphodiesterase 1C calmodulin dependent 70kDa.
Specificity:
●
Rabbit Polyclonal IgG, affinity purified by Protein A.
●
Reacts with:
(predicted: )
●
Immunogen: KLH conjugated synthetic peptide derived from human PDE1C.
●
Predicted Molecular Weight: 81kDa.
Storage:
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Application:
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.