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PAP2c Rabbit pAb (bs-0739R)  
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50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包裝/詢價
產(chǎn)品編號 bs-0739R
英文名稱 PAP2c Rabbit pAb
中文名稱 磷脂酸磷酸酶2C抗體
別    名 PPAP2C; EC 3.1.3.4; Phosphatidic acid phosphatase 2c; Lipid phosphate phosphohydrolase 2; LPP2; PAP 2c; PAP2 G; PAP2 gamma; Phosphatidic acid phosphatase 2c; Phosphatidic acid phosphatase type 2C; Phosphatidate phosphohydrolase type 2c; Type 2 phosphatidic acid phosphatase gamma; PAP2c; PAP-2c; PAP2G; PAP2-gamma; LPP2_HUMAN; PAP2-G.  
研究領(lǐng)域 腫瘤  細胞生物  信號轉(zhuǎn)導  激酶和磷酸酶  脂蛋白  新陳代謝  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human,Mouse,Rat,Pig,Cow)
產(chǎn)品應(yīng)用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 33 kDa
檢測分子量
細胞定位 細胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human PAP2c: 81-276/288 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 The protein encoded by this gene is a member of the phosphatidic acid phosphatase (PAP) family. PAPs convert phosphatidic acid to diacylglycerol, and function in de novo synthesis of glycerolipids as well as in receptor-activated signal transduction mediated by phospholipase D. This protein is similar to phosphatidic acid phosphatase type 2A (PPAP2A) and type 2B (PPAP2B). All three proteins contain 6 transmembrane regions, and a consensus N-glycosylation site. This protein has been shown to possess membrane associated PAP activity. Three alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008].

Function:
Catalyzes the conversion of phosphatidic acid (PA) to diacylglycerol (DG). In addition it hydrolyzes lysophosphatidic acid (LPA), ceramide-1-phosphate (C-1-P) and sphingosine-1-phosphate (S-1-P). The relative catalytic efficiency is PA > C-1-P > LPA > S-1-P.

Subunit:
Homodimer.

Subcellular Location:
Membrane; Multi-pass membrane protein.

Tissue Specificity:
Found mainly in brain, pancreas and placenta.

Similarity:
Belongs to the PA-phosphatase related phosphoesterase family.

SWISS:
O43688

Gene ID:
8612

Database links:

Entrez Gene: 8612 Human

Omim: 607126 Human

SwissProt: O43688 Human



PAP2c-磷脂酸磷酸酶-2C 又稱:PAP2-gamma、PAP2-G主要用于胰島素、糖及脂肪代謝方面的研究。
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