產(chǎn)品編號 | bsm-2069M |
英文名稱 | Mouse Anti-Ketamine(4E2) antibody |
中文名稱 | 氯胺酮單克隆抗體 |
別 名 | (±)-2-(2-Chlorophenyl)-2-(methylamino)cyclohexanone hydrochloride. |
產(chǎn)品類型 | 小分子抗體 |
研究領(lǐng)域 | 神經(jīng)生物學 藥物及化合物 |
抗體來源 | Mouse |
克隆類型 | Monoclonal |
克 隆 號 | 4E2 |
交叉反應(yīng) | (predicted: Ketamine) |
產(chǎn)品應(yīng)用 | ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | .27419kDa |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated Ketamine |
亞 型 | IgG1 |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
Ketamine is a drug used in human and veterinary medicine. Its hydrochloride salt is sold as Ketanest, Ketaset, and Ketalar. Pharmacologically, ketamine is classified as an NMDA receptor antagonist.[2] At high, fully anesthetic level doses, ketamine has also been found to bind to opioid Mu receptors and sigma receptors.[3][4] Like other drugs of this class such as tiletamine and phencyclidine (PCP), it induces a state referred to as "dissociative anesthesia"[5] and is used as a recreational drug. 氯胺酮(Ketamine),又稱為開他敏、K粉,是一種非巴比妥類靜脈全麻藥。氯胺酮(ketanine)是苯環(huán)己哌啶(phencyclidine)的衍生物。臨床所用的氯胺酮是右旋氯胺酮和左旋氯胺酮兩對映異構(gòu)體的消旋體。實驗研究表明,右旋氯胺酮的麻醉效價為左旋氯胺酮的4倍,而蘇醒期精神運動反應(yīng)卻較少。市售氯胺酮為其鹽酸鹽,易溶于水,pH3.5~5.5,pK a 7.5。 由于氯胺酮具有一定的精神依賴性,易使人形成癮癖,便成為娛樂場所的常用毒品。這種外觀純白的細結(jié)晶體為鼻吸或溶于飲料后飲用,能興奮心血管,吸食過量可致死。吸食者在其作用下會瘋狂搖頭,可能造成心力、呼吸衰竭。吸食過量或長期吸食,心、肺、神經(jīng)都可能造成致命損傷。 充分認識“K粉”濫用對人體和社會造成的危害。不要輕信“K粉”不會成癮的說法而去嘗試,目前我國已將“K粉”列入和冰毒、嗎啡、度冷丁等同屬于毒品類,并嚴厲打擊販賣及吸食“K粉”。 |
1、抗體溶解方法 | |
2、抗體修復方式 | |
3、常用試劑的配制 | |
4、免疫組化操作步驟 | |
5、免疫組化問題解答 | |
6、Western Blotting 操作步驟 | |
7、Western Blotting 問題解答 | |
8、關(guān)于肽鏈的設(shè)計 | |
9、多肽的溶解與保存 | |
10、酶標抗體效價測定程序 | |