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Zfp91 Rabbit pAb (bs-1941R)  
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產(chǎn)品編號 bs-1941R
英文名稱 Zfp91 Rabbit pAb
中文名稱 白血病相關新基因抗體
別    名 zinc finger protein 91; FKSG11; HGNC:14983; PZF; zinc finger protein 91 homolog(mouse); zinc finger protein homologous to mouse Zfp91; ZFP91_HUMAN.  
研究領域 腫瘤  細胞生物  免疫學  染色質和核信號  神經(jīng)生物學  細胞凋亡  轉錄調節(jié)因子  結合蛋白  細胞分化  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Mouse,Rat (predicted: Human,Pig,Sheep,Cow,Chicken,Dog,Horse)
產(chǎn)品應用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 63 kDa
檢測分子量
細胞定位 細胞核 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Zfp91: 301-400/570 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 The protein encoded by ZFP91 is a member of the zinc finger family of proteins. This protein contains C2H2 type domains, which are the classical zinc finger domains found in numerous nucleic acid-binding proteins. May be involved in transcriptional regulation. May play an important role in cell proliferation and/or anti-apoptosis Found in all the examined tissues including brain, heart, kidney, lung, liver, spleen, thymus, skeletal muscle, ovary and testis. Belongs to the krueppel C2H2-type zinc-finger protein family.

Function:
Atypical E3 ubiquitin-protein ligase that mediates 'Lys-63'-linked ubiquitination of MAP3K14/NIK, leading to stabilize and activate MAP3K14/NIK. It thereby acts as an activator of the non-canonical NF-kappa-B2/NFKB2 pathway. May also play an important role in cell proliferation and/or anti-apoptosis.

Subunit:
Interacts with MAP3K14/NIK.

Subcellular Location:
Nucleus.

Tissue Specificity:
Expressed ubiquitously, particularly at high level in testis. Isoform 2 is testis specific.

Similarity:
Belongs to the krueppel C2H2-type zinc-finger protein family.
Contains 5 C2H2-type zinc fingers.

SWISS:
Q96JP5

Gene ID:
80829

Database links:

Entrez Gene: 80829 Human

Entrez Gene: 109910 Mouse

Entrez Gene: 246282 Rat

SwissProt: Q96JP5 Human

SwissProt: Q62511 Mouse

Unigene: 524920 Human

Unigene: 290924 Mouse

Unigene: 1772 Rat



產(chǎn)品圖片
Paraformaldehyde-fixed, paraffin embedded (Mouse testis); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; A
Paraformaldehyde-fixed, paraffin embedded (Rat testis); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Ant
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