產(chǎn)品編號(hào) | bs-6563R |
英文名稱 | Rabbit Anti-NMT1 antibody |
中文名稱 | 豆蔻?;D(zhuǎn)移酶1抗體 |
別 名 | Alternative, short form NMT S; Glycylpeptide N tetradecanoyltransferase 1; Long form, NMT L; Myristoyl CoA:protein N myristoyltransferase 1; N myristoyltransferase 1; NMT; NMT1; Peptide N myristoyltransferase 1; Type I N myristoyltransferase; NMT1_HUMAN. |
研究領(lǐng)域 | 腫瘤 細(xì)胞生物 干細(xì)胞 腫瘤細(xì)胞生物標(biāo)志物 |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | (predicted: Human,Mouse,Rat,Rabbit,Pig,Sheep,Cow,Chicken,Dog) |
產(chǎn)品應(yīng)用 | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 57kDa |
細(xì)胞定位 | 細(xì)胞漿 |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human NMT1: 231-330/496 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
Myristate, a rare 14-carbon saturated fatty acid, is cotranslationally attached by an amide linkage to the N-terminal glycine residue of cellular and viral proteins with diverse functions. N-myristoyltransferase (NMT; EC 2.3.1.97) catalyzes the transfer of myristate from CoA to proteins. N-myristoylation appears to be irreversible and is required for full expression of the biologic activities of several N-myristoylated proteins, including the alpha subunit of the signal-transducing guanine nucleotide-binding protein (G protein) GO (GNAO1; MIM 139311) Function: Adds a myristoyl group to the N-terminal glycine residue of certain cellular and viral proteins. Subcellular Location: Cytoplasm. Tissue Specificity: Heart, gut, kidney, liver and placenta. Similarity: Belongs to the NMT family. SWISS: P30419 Gene ID: 4836 Database links: Entrez Gene: 4836 Human Omim: 160993 Human SwissProt: P30419 Human Unigene: 532790 Human |