| 產(chǎn)品編號(hào) | bs-6787R |
| 英文名稱 | SLC26A4 Rabbit pAb |
| 中文名稱 | 鈉碘單獨(dú)轉(zhuǎn)運(yùn)蛋白SLC26A4抗體 |
| 別 名 | PDS; deafness, autosomal recessive 4; DFNB4; EVA; NSRD4; Pendred syndrome; Pendred syndrome homolog; Pendrin; S26A4_HUMAN; SLC26A4; Sodium independent chloride/iodide transporter; Sodium-independent chloride/iodide transporter; Solute carrier family 26 member 4. |
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Specific References (2) | bs-6787R has been referenced in 2 publications.
[IF=3.164] Yamauchi T et al. Na+-Cl- cotransporter-mediated chloride uptake contributes to hypertension and renal damage in aldosterone-infused rats.Am J Physiol Renal Physiol. 2018 Aug 1;315(2):F300-F312. WB ; Rat.
[IF=2.765] Andharia et al. Electrophysiological properties of anion exchangers in the luminal membrane of guinea pig pancreatic duct cells. (2018) Pflugers.Arch. 470:897-907 IHC/WB ; guinea pigs.
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| 研究領(lǐng)域 | 細(xì)胞生物 神經(jīng)生物學(xué) 信號(hào)轉(zhuǎn)導(dǎo) 轉(zhuǎn)錄調(diào)節(jié)因子 通道蛋白 細(xì)胞表面分子 |
| 抗體來(lái)源 | Rabbit |
| 克隆類(lèi)型 | Polyclonal |
| 交叉反應(yīng) | Human (predicted: Mouse,Rat,Pig,Cow,Dog,Horse) |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000,Flow-Cyt=1ug/test,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 93 kDa |
| 檢測(cè)分子量 | |
| 細(xì)胞定位 | 細(xì)胞膜 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human Solute carrier family 26 member 4: 301-400/780 <Extracellular> |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
This gene belongs to the solute carrier 26 family, whose members encode anion transporter proteins. This particular family member encodes a protein involved in transporting chloride, oxalate, sulfate and bicarbonate. Several alternatively spliced transcript variants of this gene, encoding distinct isoforms, have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Jul 2008]. Function: Sodium-independent transporter of chloride and iodide. Subcellular Location: Membrane; Multi-pass membrane protein. Tissue Specificity: High expression in adult thyroid, lower expression in adult and fetal kidney and fetal brain. Not expressed in other tissues. DISEASE: Defects in SLC26A4 are the cause of deafness autosomal recessive type 4 (DFNB4) [MIM:600791]; also known as vestibular aqueduct syndrome (EVA). DFNB4 is a form of sensorineural hearing loss. Sensorineural deafness results from damage to the neural receptors of the inner ear, the nerve pathways to the brain, or the area of the brain that receives sound information. DFNB4 is associated with an enlarged vestibular aqueduct. Similarity: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. Contains 1 STAS domain. SWISS: O43511 Gene ID: 5172 Database links: UniProtKB/Swiss-Prot: O43511.1 |
| 產(chǎn)品圖片 |
Sample:
Lane 1: Human TT cell lysates
Lane 2: Human U251 cell lysates
Primary: Anti-SLC26A4 (bs-6787R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 93 kDa
Observed band size: 93 kDa
Blank control: U87MG. Primary Antibody (green line): Rabbit Anti-SLC26A4 antibody (bs-6787R) Dilution: 1μg /10^6 cells; Isotype Control Antibody (orange line): Rabbit IgG . Secondary Antibody : Goat anti-rabbit IgG-PE Dilution: 1μg /test. The
Black line : Positive blank control (U87MG); Negative blank control (Molt4）
Green line : Primary Antibody (Rabbit Anti-SLC26A4 antibody (bs-6787R) )
Orange line：Isotype Control Antibody (Rabbit IgG) .
Blue line : Secondary Antibody (Goat anti-rabbit I
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