| 產(chǎn)品編號 | bs-7524R |
| 英文名稱 | Rabbit Anti-Thrombospondin 2 antibody |
| 中文名稱 | 血小板反應(yīng)蛋白2/凝血酶敏感蛋白2抗體 |
| 別 名 | THBS2; Thrombospondin-2; Thrombospondin2; TSP2; TSP2_HUMAN. |
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Specific References (3) | bs-7524R has been referenced in 3 publications.
[IF=4.638] Li Jianxiong. et al. Whole-exome mutational landscape and molecular marker study in mucinous and clear cell ovarian cancer cell lines 3AO and ES2. BMC CANCER. 2023 Dec;23(1):1-13 WB,IF ; Human.
[IF=2.22] Ken-Go Hayashi. et al. Differential expression of pro- and anti-angiogenic factors in the endometrium between repeat breeder and normally fertile cows. ANIM REPROD SCI. 2023 Jul;254:107265 IHC ; Bovine.
[IF=1.33] Chen, Junying, et al. "MiR-1246 promotes SiHa cervical cancer cell proliferation, invasion, and migration through suppression of its target gene thrombospondin 2." Archives of Gynecology and Obstetrics (2014): 1-8. WB ; Human.
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| 研究領(lǐng)域 | 腫瘤 心血管 細(xì)胞生物 細(xì)胞因子 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Human (predicted: Mouse,Rat,Horse) |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 128kDa |
| 細(xì)胞定位 | 細(xì)胞外基質(zhì) 分泌型蛋白 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human Thrombospondin 2: 201-300/1172 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
Adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. Can bind to fibrinogen, fibronectin, laminin and type V collagen. Function: Adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. Ligand for CD36 mediating antiangiogenic properties. Subunit: Homotrimer; disulfide-linked. Interacts (via the TSP type I repeats) with CD36; the interaction conveys an antiangiogenic effect. Interacts (via the TSP type I repeats) with HRG; the interaction blocks the antiangiogenic effect of THBS2 with CD36. Can bind to fibrinogen, fibronectin, laminin and type V collagen. Tissue Specificity: High expression in invertebral disk tissue. DISEASE: Genetic variations in THBS2 may be a cause of susceptibility to intervertebral disk disease (IDD) [MIM:603932]; also known as lumbar disk herniation (LDH). IDD is one of the most common musculo-skeletal disorders and the predominant cause of low-back pain and unilateral leg pain. Similarity: Belongs to the thrombospondin family. Contains 2 EGF-like domains. Contains 1 laminin G-like domain. Contains 1 TSP C-terminal (TSPC) domain. Contains 3 TSP type-1 domains. Contains 8 TSP type-3 repeats. Contains 1 VWFC domain. SWISS: P35442 Gene ID: 7058 Database links: Entrez Gene: 7058 Human Entrez Gene: 21826 Mouse Omim: 188061 Human SwissProt: P35440 Chicken SwissProt: P35442 Human SwissProt: Q03350 Mouse Unigene: 797 Chicken Unigene: 5522 Cow Unigene: 371147 Human Unigene: 26688 Mouse |
| 產(chǎn)品圖片 |
Sample:
MG63(Human) Cell Lysate at 40 ug
Primary: Anti-Thrombospondin 2 (bs-7524R) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 128 kD
Observed band size: 128 kD
Sample:
HUVEC(Human) Cell Lysate at 40 ug
Primary: Anti-Thrombospondin 2 (bs-7524R) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 128 kD
Observed band size: 128 kD
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