產(chǎn)品編號 | bs-7528R |
英文名稱 | Rabbit Anti-CTRP1 antibody |
中文名稱 | 補體C1q腫瘤壞死因子相關(guān)蛋白1抗體 |
別 名 | C1q and tumor necrosis factor related protein 1; C1QT1_HUMAN; C1QTNF1 antibody Complement C1q tumor necrosis factor related protein 1; Complement C1q tumor necrosis factor-related protein 1; CTRP 1; FLJ90694; G protein coupled receptor interacting protein 1; G protein-coupled receptor-interacting protein; GIP; ZSIG37; G protein coupled receptor interacting protein 1. |
研究領(lǐng)域 | 心血管 信號轉(zhuǎn)導(dǎo) 糖尿病 |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | (predicted: Human,Mouse,Rat,Sheep,Cow,Chicken,Dog,Horse) |
產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 29kDa |
細胞定位 | 分泌型蛋白 |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human CTRP1: 51-150/281 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
CTRP1 enhances the production of aldosterone. CTRP1 was highly expressed in obese subjects as well as up-regulated in hypertensive patients, CTRP1 may be a newly identified molecular link between obesity and hypertension. Subcellular Location: Secreted (Potential). Similarity: Contains 1 C1q domain. Contains 1 collagen-like domain. SWISS: Q9BXJ1 Gene ID: 114897 Database links: Entrez Gene: 114897 Human Entrez Gene: 56745 Mouse GenBank: NP_940995 Human Omim: 610365 Human SwissProt: Q9BXJ1 Human SwissProt: Q9QXP7 Mouse Unigene: 201398 Human Unigene: 23845 Mouse Unigene: 53880 Rat Unigene: 82211 Rat 補體Clq TNF相關(guān)蛋白1(complement-Clq TNF-related protein 1,CTRP1)屬于CTRP超家族成員之一,能在多種組織細胞表達,包含一個 N-末端的信號肽,一個短的可變結(jié)構(gòu)域,一個膠原結(jié)構(gòu)域和一個C-末端的球形結(jié)構(gòu)域,從而在調(diào)節(jié)物質(zhì)代謝、炎癥免疫、阻止血小板聚集和抗血栓等方面發(fā)揮著重要的生物學(xué)功能. |