產(chǎn)品編號 | bs-7057R |
英文名稱 | Rabbit Anti-Glucokinase regulatory protein antibody |
中文名稱 | 葡萄糖激酶調(diào)節(jié)蛋白抗體 |
別 名 | FGQTL5; GCKR; GCKR_HUMAN; GKRP; GLRE; glucokinase (hexokinase 4) regulator; Glucokinase regulator; Glucokinase regulatory protein; OTTHUMP00000158533. |
研究領(lǐng)域 | 腫瘤 心血管 細(xì)胞生物 信號轉(zhuǎn)導(dǎo) 轉(zhuǎn)錄調(diào)節(jié)因子 糖尿病 |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | Rat (predicted: Human,Mouse,Rabbit,Pig,Dog,Horse) |
產(chǎn)品應(yīng)用 | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 69kDa |
細(xì)胞定位 | 細(xì)胞核 |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human GCKR: 121-220/625 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
Inhibits glucokinase by forming an inactive complex with this enzyme. Tissue Specificity: Found in liver and pancreas. Not detected in muscle, brain, heart, thymus, intestine, uterus, adipose tissue, kidney, adrenal, lung or spleen. Similarity: Belongs to the GCKR family. Contains 2 SIS domains. SWISS: Q14397 Gene ID: 2646 Database links: Entrez Gene: 2646 Human Entrez Gene: 231103 Mouse Omim: 600842 Human SwissProt: Q14397 Human SwissProt: Q91X44 Mouse Unigene: 89771 Human Unigene: 100043 Mouse |
產(chǎn)品圖片 |
Tissue/cell: rat liver tissue; 4% Paraformaldehyde-fixed and paraffin-embedded;
Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min;
Incubation: Anti-GCKR/Glucokinase regulatory protein Polyclonal Antibody, Unconjugated (bs-7057R) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining
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