| 產(chǎn)品編號 | bs-7810R |
| 英文名稱 | MFAP1 Rabbit pAb |
| 中文名稱 | 微原纖維膠原相關(guān)蛋白1抗體 |
| 別 名 | MFAP1 is an extracellular protein associated with elastic fiber microfibrils. |
| 研究領(lǐng)域 | 細(xì)胞生物 信號轉(zhuǎn)導(dǎo) 細(xì)胞周期蛋白 細(xì)胞骨架 細(xì)胞外基質(zhì) |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Human,Mouse (predicted: Rat,Pig,Cow,Chicken) |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 52 kDa |
| 檢測分子量 | |
| 細(xì)胞定位 | 細(xì)胞外基質(zhì) 分泌型蛋白 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human MFAP1: 31-120/439 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
Microfibrils are an important component of the extracellular matrix of many tissues and can either associate with or without elastin. Several microfibril associated proteins (MFAPs) have been cloned, including MFAP1, MFAP3 and MFAP4. The MFAP1 and MFAP3 genes are localized near the fibrillin genes FBN1 and FBN2, respectively. Mutations in FBN1 are linked to Marfan syndrome. Mutations in FBN2 have been linked to congenital contractural arachnodactyly. This suggests roles for MFAP1 and MFAP3 in heritable diseases affecting microfibrils. Deletion of MFAP4 was found in 30 of 31 patients with Smith-Magenis syndrome (SMS), a clinically recognizable multiple congenital anomaly/mental retardation syndrome. Function: Component of the elastin-associated microfibrils. Subcellular Location: Secreted, extracellular space, extracellular matrix. Similarity: Belongs to the MFAP1 family. SWISS: P55081 Gene ID: 4236 Database links: Entrez Gene: 4236 Human Entrez Gene: 100034361 Mouse Entrez Gene: 67532 Mouse Omim: 600215 Human SwissProt: 5EA98 Cow SwissProt: P55081 Human SwissProt: Q9CQU1 Mouse Unigene: 61418 Human Unigene: 270393 Mouse Unigene: 440764 Mouse |
| 產(chǎn)品圖片 |
Sample: Lymph node (Mouse) Lysate at 40 ug
Primary: Anti-MFAP1 (bs-7810R) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 52 kD
Observed band size: 52 kD
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