| 產(chǎn)品編號(hào) | bs-8158R |
| 英文名稱 | Rabbit Anti-HCV NS5A transactivated protein 8 antibody |
| 中文名稱 | 丙肝病毒NS5A反轉(zhuǎn)錄蛋白8抗體 |
| 別 名 | BTB (POZ) domain containing 1; BTB domain containing 1; BTB/POZ domain containing protein 1; BTBD 1; C15orf1; HCV NS5A transactivated protein 8; Hepatitis C virus NS5A transactivated protein 8; NS5ATP8; BTBD1_HUMAN. |
| 研究領(lǐng)域 | 細(xì)胞生物 免疫學(xué) 細(xì)胞周期蛋白 轉(zhuǎn)錄調(diào)節(jié)因子 細(xì)菌及病毒 細(xì)胞分化 |
| 抗體來(lái)源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human,Mouse,Rat,Pig,Sheep,Cow,Dog,Horse) |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 53kDa |
| 細(xì)胞定位 | 細(xì)胞漿 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human BTBD1/HCV NS5A transactivated protein 8: 401-482/482 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
BTBD1 contains a proline-rich region and a BTB/POZ domain which are typically involved in protein-protein interactions. The C-terminus of BTBD1 binds topoisomerase I and BTBD1 also interacts with TRIM5 isoform Delta. BTBD1 localizes to cytoplasmic bodies and is essential for myogenic differentiation. Function: Probable substrate-specific adapter of an E3ubiquitin-protein ligase complex which mediates the ubiquitinationand subsequent proteasomal degradation of target proteins. Subunit: Interacts with topoisomerase 1 and with TRIM5 isoformDelta. Interacts with CUL3. Subcellular Location: Cytoplasm, P-body. Note=Cytoplasmic bodies. Tissue Specificity: Ubiquitous; higher levels in heart andskeletal muscle. Similarity: Contains 1 BTB (POZ) domain. SWISS: Q9H0C5 Gene ID: 53339 Database links: Entrez Gene: 53339 Human Entrez Gene: 83962 Mouse Omim: 608530 Human SwissProt: Q9H0C5 Human SwissProt: P58544 Mouse Unigene: 459149 Human Unigene: 439893 Mouse |
