| 產(chǎn)品編號(hào) | bs-8469R |
| 英文名稱 | Rabbit Anti-FBXL17 antibody |
| 中文名稱 | FBXL17蛋白抗體 |
| 別 名 | F box and leucine rich repeat protein 17; F box only protein 13; F box/LRR repeat protein 17; F-box and leucine-rich repeat protein 17; F-box only protein 13; F-box/LRR-repeat protein 17; FBL17; FBX13; Fbxl17; FBXO13; FBXL13; FXL17_HUMAN; DKFZP434C1715. |
| 研究領(lǐng)域 | 細(xì)胞生物 免疫學(xué) 泛素 |
| 抗體來(lái)源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Human (predicted: Mouse,Rat,Rabbit,Pig,Sheep,Cow,Chicken,Dog,Horse) |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 76kDa |
| 細(xì)胞定位 | 細(xì)胞核 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human FBXL17: 451-550/701 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
Members of the F-box protein family, such as FBXL17, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM, Mar 2008] Function: Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. Subunit: Interacts with SKP1 and CUL1 Similarity: Contains 1 F-box domain. SWISS: Q9UF56 Gene ID: 64839 Database links: Entrez Gene: 64839 Human Entrez Gene: 50758 Mouse Omim: 609083 Human SwissProt: Q9UF56 Human SwissProt: Q9QZN1 Mouse Unigene: 657225 Human Unigene: 721914 Human Unigene: 136366 Mouse |
| 產(chǎn)品圖片 |
Sample: MDA-MB-231 cell (Human) Lysate at 30 ug
Primary: Anti-FBXL17 (bs-8469R)at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 76kD
Observed band size: 76kD
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