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APBB2 Rabbit pAb (bs-11627R)  
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50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包裝/詢價
產品編號 bs-11627R
英文名稱 APBB2 Rabbit pAb
中文名稱 鐵蛋白Fe65樣蛋白1抗體
別    名 Amyloid beta(A4) precursor protein-binding, family B, member 2(Fe65 like); Amyloid beta A4 precursor protein binding family B member 2; Amyloid beta A4 precursor protein-binding family B member 2; APBB 2; APBB2; APBB2_HUMAN; Fe65 like 1; Fe65 like; Fe65 l  
研究領域 細胞生物  神經生物學  信號轉導  Alzheimer's  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human,Mouse,Rat,Rabbit,Pig,Cow,Dog,Horse)
產品應用 WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 83 kDa
檢測分子量
細胞定位 細胞核 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human APBB2: 251-350/758 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 The protein encoded by this gene interacts with the cytoplasmic domains of amyloid beta (A4) precursor protein and amyloid beta (A4) precursor-like protein 2. This protein contains two phosphotyrosine binding (PTB) domains, which are thought to function in signal transduction. Polymorphisms in this gene have been associated with Alzheimer's disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]

Function:
May modulate the internalization of beta-amyloid precursor protein.

Subunit:
Binds to the intracellular domain of the beta-amyloid precursor protein.

Similarity:
Contains 2 PID domains.
Contains 1 WW domain.

SWISS:
Q92870

Gene ID:
323

Database links:

Entrez Gene: 323 Human

Entrez Gene: 11787 Mouse

Omim: 602710 Human

SwissProt: Q92870 Human

SwissProt: Q9DBR4 Mouse

Unigene: 479602 Human

Unigene: 482700 Mouse

Unigene: 5159 Mouse



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