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OSR1 + OSR2 Rabbit pAb (bs-12377R)  
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產(chǎn)品編號 bs-12377R
英文名稱 OSR1 + OSR2 Rabbit pAb
中文名稱 OSR1/OSR2蛋白抗體
別    名 FLJ90037; Odd skipped related 2; Odd skipped related 2A protein; Odd-skipped related; odd-skipped related 2(Drosophila); Osr2; OSR2_HUMAN; Protein odd-skipped-related 2; ODD; Odd skipped Drosophila homolog; Odd skipped homolog; Odd skipped related 1(Drosophila); Odd skipped related 1; Odd skipped related 1 Drosophila; Odd1; Protein odd skipped related 1; OSR1_HUMAN.  
研究領域 細胞生物  發(fā)育生物學  干細胞  鋅指蛋白  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human,Mouse,Rat (predicted: Pig,Sheep,Cow,Dog,Horse,Danio rerio)
產(chǎn)品應用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 35 kDa
檢測分子量
細胞定位 細胞核 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human OSR2 and OSR1: 181-280/312 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 OSR2 is a 312 amino acid protein that contains five zinc finger domains. It is expressed in the kidneys, skeletal muscle, testis, and mouse embryos and may be involved in transcriptional activity and osteoblast function. The expression of OSR2 is regulated by C/EBP regulatory elements. OSR2 plays a role in regulating palatal development and expression of alkaline phosphatase. Two isoforms, OSR2A and OSR2B, are produced due to alternative splicing. OSR2B is 36 amino acids shorter than OSR2A and contains only three zinc finger motifs. Both isoforms localize to the nucleus and are thought to exhibit opposite transcriptional activities. Mutations in the gene encoding OSR2 can alter the gene expression of Pax-9 and TGF beta3.

Subcellular Location:
Nucleus.

Similarity:
Belongs to the Odd C2H2-type zinc-finger protein family.
Contains 5 C2H2-type zinc fingers.

SWISS:
Q8TAX0

Gene ID:
130497

Database links:

Entrez Gene: 539430 Cow

Entrez Gene: 130497 Human

Entrez Gene: 23967 Mouse

Entrez Gene: 298878 Rat

Omim: 608891 Human

SwissProt: Q08DS3 Cow

SwissProt: Q8TAX0 Human

SwissProt: Q9WVG7 Mouse

SwissProt: B0K011 Rat

Entrez Gene: 116039 Human

Entrez Gene: 107587 Mouse

Entrez Gene: 315039 Rat

Omim: 611297 Human

SwissProt: Q8N2R0 Human

SwissProt: Q91ZD1 Mouse

SwissProt: Q6AY34 Rat

Unigene: 253247 Human

Unigene: 46336 Mouse

Unigene: 13228 Rat



產(chǎn)品圖片
Paraformaldehyde-fixed, paraffin embedded (human testis); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; I
Tissue/cell: mouse embryo tissue ; 4% Paraformaldehyde-fixed and paraffin-embedded; Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goa
Paraformaldehyde-fixed, paraffin embedded (Rat kidney); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; An
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