| 產(chǎn)品編號(hào) | bs-12404R |
| 英文名稱 | Rabbit Anti-FJX1 antibody |
| 中文名稱 | 四連接同源蛋白FJX1抗體 |
| 別 名 | FJX1 four jointed box 1 Drosophila; FLJ22416; FLJ25593; Four jointed box 1; Four jointed box 1 Drosophila; Four jointed protein homolog; four-jointed box protein 1; Putative secreted ligand homologous to FJX1; FJX1_HUMAN. |
| 研究領(lǐng)域 | 細(xì)胞生物 染色質(zhì)和核信號(hào) 信號(hào)轉(zhuǎn)導(dǎo) |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human,Mouse,Rat,Pig,Sheep,Cow,Dog,Horse) |
| 產(chǎn)品應(yīng)用 | ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 46kDa |
| 細(xì)胞定位 | 分泌型蛋白 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human FJX1: 301-400/437 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
FJX1 is a 437 amino acid protein that belongs to the FJX1/FJ family. FJX1 is highly conserved in vertebrates and is expressed in the peripheral nervous system, epithelial cells of multiple organs and during limb development. FJX1 is processed and secreted as a presumptive ligand and may act as an inhibitor of dendrite extension and branching. In Drosophila, FJX1 is important for growth and differentiation of legs and wings, and for proper development of the eyes. FAT4, an essential gene that has a key role in vertebrate PCP (planar cell polarity), represses FJX1 expression which may lead to cystic diseases in humans. Function: FJX1 is the human ortholog of mouse and Drosophila four-jointed gene product. The Drosophila protein is important for growth and differentiation of legs and wings, and for proper development of the eyes. The exact function of this gene in humans is not known. Subcellular Location: Secreted Post-translational modifications: Glycosylated (By similarity). Undergoes proteolytic cleavage (By similarity). Similarity: Belongs to the FJX1/FJ family. SWISS: Q86VR8 Gene ID: 24147 Database links: Entrez Gene: 24147 Human Omim: 612206 Human SwissProt: Q86VR8 Human |
