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Rabbit Anti-Blood Group Lewis b  antibody (bs-12871R)  
~~~促銷(xiāo)代碼KT202411~~~
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100ul/1980.00元
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大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-12871R
英文名稱 Rabbit Anti-Blood Group Lewis b  antibody
中文名稱 粘蛋白/巖藻糖基轉(zhuǎn)移酶3抗體
別    名 Blood group Lewis alpha-4-fucosyltransferase; Fucosyltransferase 3; Fucosyltransferase III; FucT-III; FUT3; FUT3_HUMAN; Galactoside 3(4)-L-fucosyltransferase; gastric mucin; leB; lewis antigen system; lewis b; Lewis B Blood Group antigen; Lewis FT; lewisb; major airway glycoprotein; MUC5; mucin 5, subtypes A and C, tracheobronchial/gastric; mucin 5AC, oligomeric mucus/gel-forming; mucin 5AC, oligomeric mucus/gel-forming pseudogene; mucin-5 subtype AC, tracheobronchial; TBM; tracheobronchial mucin.  
研究領(lǐng)域 細(xì)胞生物  細(xì)胞粘附分子  糖蛋白  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human)
產(chǎn)品應(yīng)用 IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 42kDa
細(xì)胞定位 細(xì)胞漿 細(xì)胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Blood Group Lewis b: 165-280/361 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 Glycosyltransferases that mediate the regio- and stereoselective transfer of sugars, such as the fucosyltransferases, determine cell surface-carbohydrate profiles, which is an essential interface for biological recognition processes. Fucosyltransferases catalyze the covalent association of fucose to different positional linkages in sugar acceptor molecules. The carbohydrate moieties generated and covalently attached to cell surfaces are necessary to ensure a surface contour that satisfies physiological roles, which are reliant on adhesion molecules such as Selectins (1-3). Hematopoietic lineages rely on Fucosyltransferases to confer a surface carbohydrate phenotype, which mediates proper cell adhesion molecule recruitment and cell trafficking (4-6). Blood Group Lewis b is a carbohydrate determinant carried on both glycolipids and glycoproteins.

Function:
Blood group Lewis b is a carbohydrate determinant carried on both glycolipids and glycoproteins, detected on erythrocytes, certain epithelial cells, and in secretions of certain individuals.

Subcellular Location:
Plasma membrane - adsorbed onto the surface of erythrocytes.

Tissue Specificity:
Highly expressed in stomach, colon, smallintestine, lung and kidney and to a lesser extent in salivarygland, bladder, uterus and liver.

Similarity:
Belongs to the glycosyltransferase 10 family.

SWISS:
P21217

Gene ID:
2525

Database links:

Entrez Gene: 2525 Human

Omim: 111100 Human

SwissProt: P21217 Human

Unigene: 169238 Human



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