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APR3 Rabbit pAb (bs-13814R)  
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產(chǎn)品編號(hào) bs-13814R
英文名稱(chēng) APR3 Rabbit pAb
中文名稱(chēng) 凋亡相關(guān)蛋白3抗體
別    名 Apoptosis related protein 3; Apoptosis related protein APR 3; APR 3; Chromosome 2 open reading frame 28; HSPC013; p18; PRO240; C2orf28; ARAID_HUMAN.  
研究領(lǐng)域 細(xì)胞生物  免疫學(xué)  細(xì)胞凋亡  細(xì)胞分化  
抗體來(lái)源 Rabbit
克隆類(lèi)型 Polyclonal
交叉反應(yīng) Human,Mouse (predicted: Dog)
產(chǎn)品應(yīng)用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 22 kDa
檢測(cè)分子量
細(xì)胞定位 細(xì)胞核 細(xì)胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human APR3: 51-150/229 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 This gene is thought to be involved in apoptosis, and may also be involved in hematopoietic development and differentiation. The use of alternative splice sites and promotors result in multiple transcript variants encoding different isoforms.[provided by RefSeq, Dec 2009]

Function:
Promotes osteoblast cell differentiation and terminal mineralization. Plays a role in inducing the cell cycle arrest via inhibiting CCND1 expression in all-trans-retinoic acid (ATRA) signal pathway.

Subunit:
Interacts with NELL1; the interaction promotes osteoblastic differentiation and mineralization.

Subcellular Location:
Cell membrane; Single pass membrane protein.

Tissue Specificity:
Weakly expressed in hematopoietic cell lines.

Similarity:
Contains 1 EGF-like domain.

SWISS:
Q6UW56

Gene ID:
51374

Database links:

Entrez Gene: 51374 Human

SwissProt: Q6UW56 Human



產(chǎn)品圖片
Paraformaldehyde-fixed, paraffin embedded (Mouse brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (APR3) Polyclonal Antibody, Unconjugated (bs-13814R) at 1:500 overnight at 4°C, followed by a conjugated secondary (sp-0023) for 20 minutes and DAB staining.
Paraformaldehyde-fixed, paraffin embedded (Human kidney); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (APR3) Polyclonal Antibody, Unconjugated (bs-13814) at 1:400 overnight at 4°C, followed by a conjugated secondary (sp-0023) for 20 minutes and DAB staining.
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