產(chǎn)品編號(hào) | bs-16904R |
英文名稱 | Rabbit Anti-KCNK5 antibody |
中文名稱 | 鉀離子通道蛋白5抗體 |
別 名 | Acid sensitive potassium channel protein TASK 2; Acid-sensitive potassium channel protein TASK-2; FLJ11035; K2p5.1; KCNK 5; KCNK5; KCNK5_HUMAN; Potassium channel subfamily K member 1; Potassium channel subfamily K member 5; TASK 2; TASK2; TWIK related acid sensitive K(+) channel 2; TWIK related acid sensitive K+ channel 2; TWIK-related acid-sensitive K(+) channel 2. |
研究領(lǐng)域 | 腫瘤 細(xì)胞生物 神經(jīng)生物學(xué) 通道蛋白 細(xì)胞膜受體 |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | (predicted: Human,Mouse,Rat,Sheep,Cow,Chicken,Horse) |
產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 56kDa |
細(xì)胞定位 | 細(xì)胞膜 |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human KCNK5: 101-200/499 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
This gene encodes one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains. The message for this gene is mainly expressed in the cortical distal tubules and collecting ducts of the kidney. The protein is highly sensitive to external pH and this, in combination with its expression pattern, suggests it may play an important role in renal potassium transport. [provided by RefSeq, Jul 2008] Function: pH-dependent, voltage insensitive, outwardly rectifying potassium channel. Outward rectification is lost at high external K(+) concentrations. Subcellular Location: Membrane. Tissue Specificity: Abundant expression in kidney, also detected in liver, placenta and small intestine. In the kidney, expression is restricted to the distal tubules and collecting ducts. Not expressed in proximal tubules or glomeruli. Similarity: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. SWISS: O95279 Gene ID: 8645 Database links: Entrez Gene: 8645 Human Entrez Gene: 16529 Mouse Omim: 603493 Human SwissProt: O95279 Human SwissProt: Q9JK62 Mouse Unigene: 444448 Human Unigene: 68998 Mouse |