| 產(chǎn)品編號 | bs-17523R |
| 英文名稱 | OSCAR Rabbit pAb |
| 中文名稱 | 破骨細(xì)胞相關(guān)受體抗體 |
| 別 名 | hOSCAR; hOSCARM2; hOSCARM3; mOSCAR; Oscar; Oscar protein; OSCAR_HUMAN; OSCARS1; OSCARS2; Osteoclast associated immunoglobulin like receptor; Osteoclast associated receptor; Osteoclast-associated immunoglobulin-like receptor; Osteoclast-associated receptor; PIgR-3; PIGR3; Poly Ig receptor 3; Poly-Ig receptor 3; Polymeric immunoglobulin receptor 3. |
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Specific References (2) | bs-17523R has been referenced in 2 publications.
[IF=3.448] Ma Q et al. Non‐coenzyme role of vitamin B1 in RANKL‐induced osteoclastogenesis and ovariectomy induced osteoporosis. J Cell Biochem. 2020 Feb 26. WB ; mouse.
[IF=3.266] Ma Q et al. Vitamin B5 inhibit RANKL induced osteoclastogenesis and ovariectomy induced osteoporosis by scavenging ROS generation. Am J Transl Res. 2019 Aug 15;11(8):5008-5018. eCollection 2019. WB ; Mouse.
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| 研究領(lǐng)域 | 細(xì)胞生物 免疫學(xué) 細(xì)胞類型標(biāo)志物 t-淋巴細(xì)胞 b-淋巴細(xì)胞 細(xì)胞骨架 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human,Mouse,Rat) |
| 產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 28 kDa |
| 檢測分子量 | |
| 細(xì)胞定位 | 細(xì)胞膜 分泌型蛋白 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human OSCAR: 51-150/282 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
Osteoclasts are multinucleated cells that resorb bone and are essential for bone homeostasis. This gene encodes an osteoclast-associated receptor (OSCAR), which is a member of the leukocyte receptor complex protein family that plays critical roles in the regulation of both innate and adaptive immune responses. The encoded protein may play a role in oxidative stress-mediated atherogenesis as well as monocyte adhesion. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2013] Function: Regulator of osteoclastogenesis which plays an important bone-specific function in osteoclast differentiation. Subcellular Location: Secreted and Cell membrane. Similarity: Belongs to the leukocyte receptor complex/polymeric immunogobulin receptor (PIR/LRC) family. Contains 2 Ig-like (immunoglobulin-like) domains. SWISS: Q8IYS5 Gene ID: 126014 Database links: Entrez Gene: 126014 Human Omim: 606862 Human SwissProt: Q8IYS5 Human Unigene: 347655 Human |
