產(chǎn)品編號 | bs-18776R |
英文名稱 | Rabbit Anti-MEGF6/EGFL3 antibody |
中文名稱 | EGF蛋白樣3抗體 |
別 名 | EGF-like protein 3; EGFL3; Epidermal growth factor-like protein 3; Megf6; MEGF6_HUMAN; Multiple EGF-like domains protein 6; Multiple epidermal growth factor-like domains protein 6. |
研究領(lǐng)域 | 信號轉(zhuǎn)導(dǎo) 生長因子和激素 |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | (predicted: Human,Mouse,Rat,Sheep,Cow,Dog,GuineaPig,Horse) |
產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 158kDa |
細(xì)胞定位 | 分泌型蛋白 |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human MEGF6/EGFL3: 261-360/1541 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
EGFL3 (epidermal growth factor-like protein 3), also known as MEGF6 (multiple epidermal growth factor-like domains protein 6), is a 1,541 amino acid secreted protein containing twenty-seven EGF-like domains and an EMI domain. Existing as two alternatively spliced isoforms, the gene encoding EGFL3 maps to human chromosome 1p36.32. The largest human chromosome, spanning about 260 million base pairs and making up 8% of the human genome, chromosome 1 contains about 3,000 genes. The rare aging disease Hutchinson-Gilford progeria, as well as Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome, are associated with chromosome 1. Subcellular Location: Secreted Similarity: Contains 27 EGF-like domains. Contains 1 EMI domain. SWISS: O75095 Gene ID: 1953 Database links: Entrez Gene: 1953 Human Entrez Gene: 230971 Mouse Omim: 604266 Human SwissProt: O75095 Human SwissProt: Q80V70 Mouse Unigene: 593645 Human |