產(chǎn)品編號(hào) | bs-21145R |
英文名稱 | Rabbit Anti-RAET1G antibody |
中文名稱 | 維甲酸早期轉(zhuǎn)錄1G蛋白抗體 |
別 名 | RAET1G; RET1G_HUMAN; Retinoic acid early transcript 1G; Retinoic acid early transcript 1G protein; Retinoic acid early transcript 1G pseudogene; ULBP5. |
研究領(lǐng)域 | 細(xì)胞生物 免疫學(xué) 自然殺傷細(xì)胞 |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | (predicted: Human) |
產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 37kDa |
細(xì)胞定位 | 細(xì)胞膜 |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human RAET1G: 131-230/334 <Extracellular> |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | Preservative: 0.02% Proclin300, Constituents: 1% BSA, 0.01M PBS, pH7.4. |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
This gene encodes a member of the major histocompatibility complex (MHC) class I family of proteins. Although the encoded protein includes C-terminal transmembrane and cytoplasmic domains, proteolytic processing results in the removal of these domains and subsequent tethering to the plasma membrane by a glycosylphosphatidylinositol (GPI)-anchor. The encoded protein is one of several related ligands of the natural killer group 2, member D (NKG2D) receptor, which functions as an activating receptor in innate and adaptive immunity. This gene is present in a gene cluster on chromosome 6. [provided by RefSeq, Jul 2015] Function: Acts as a ligand for the NKG2D receptor and mediates NK cell cytotoxicity via the receptor. Subcellular Location: Cell membrane. Tissue Specificity: Highly expressed in colon and in a number of tumor cell lines. Similarity: Belongs to the MHC class I family. SWISS: Q6H3X3 Gene ID: 353091 Database links: Entrez Gene: 353091 Human Omim: 609244 Human SwissProt: Q6H3X3 Human Unigene: 558792 Human |