產(chǎn)品編號 | bs-20304R |
英文名稱 | Rabbit Anti-CSGLCAT antibody |
中文名稱 | 硫酸軟骨素聚合酶3抗體 |
別 名 | Chondroitin sulfate glucuronyltransferase; Chondroitin synthase 3; CSGlcA-T; ChSy 3; ChSy-3; CHPF2; ChPF-2; CSGLCA T; N acetylgalactosaminyl proteoglycan 3 beta glucuronosyltransferase; CHPF2_HUMAN; Chondroitin polymerizing factor 2; Chondroitin sulfate glucuronyltransferase; N acetylgalactosaminyl proteoglycan 3 beta glucuronosyltransferase; N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase. |
研究領(lǐng)域 | 細(xì)胞生物 糖蛋白 細(xì)胞類型標(biāo)志物 |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | (predicted: Human,Mouse,Rat,Rabbit,Pig,Sheep,Cow,Chicken,Horse) |
產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 86kDa |
細(xì)胞定位 | 細(xì)胞漿 細(xì)胞膜 |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human CSGLCAT: 21-120/772 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | Preservative: 0.02% Proclin300, Constituents: 1% BSA, 0.01M PBS, pH7.4. |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
CSGlcA-T is a 772 amino acid single-pass type II membrane protein of the golgi apparatus that belongs to the chondroitin N-acetylgalactosaminyltransferase family. Widely expressed and existing as two alternatively spliced isoforms, CSGlcA-T is found at highest levels in small intestine, pancreas and placenta, with lower levels in heart, brain, kidney, and skeletal muscle where it transfers glucuronic acid from UDP-glucuronic acid to N-acetylgalactosamine residues of elongating chondroitin polymers. The gene encoding CSGlcA-T maps to human chromosome 7, which houses over 1,000 genes and comprises nearly 5% of the human genome. Chromosome 7 has been linked to Osteogenesis imperfecta, Pendred syndrome and Lissencephaly. Function: Transfers glucuronic acid (GlcUA) from UDP-GlcUA to N-acetylgalactosamine residues on the non-reducing end of the elongating chondroitin polymer. Has no N-acetylgalactosaminyltransferase activity. Subcellular Location: Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein (Probable). Tissue Specificity: Ubiquitous. Highly expressed in placenta, small intestine and pancreas. Similarity: Belongs to the chondroitin N-acetylgalactosaminyltransferase family SWISS: Q9P2E5 Gene ID: 54480 Database links: Entrez Gene: 54480 Human Entrez Gene: 100910 Mouse Omim: 608037 Human SwissProt: Q9P2E5 Human Unigene: 647084 Human |