mm1313亚洲精品,欧美俄罗斯40老熟妇,欧美日韩在线观看视频在线,亚洲欧美国产激情综合在线

掃碼關(guān)注公眾號           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  人才招聘  關(guān)于我們  聯(lián)系我們
亚洲精品一区中文字幕,欧美成人精品一区二区综合
首頁 > 產(chǎn)品中心 > 一抗 > 產(chǎn)品信息
Rabbit Anti-SCARB1/Scavenger Receptor BI  antibody (bs-23977R)  
~~~促銷代碼KT202411~~~
訂購熱線:400-901-9800
訂購郵箱:sales@www.p2b3.cn
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@www.p2b3.cn
說明書: 50ul  100ul  200ul
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包裝/詢價

產(chǎn)品編號 bs-23977R
英文名稱 Rabbit Anti-SCARB1/Scavenger Receptor BI  antibody
中文名稱 高密度脂蛋白受體/清道夫受體抗體
別    名 HDL-R; High Density Lipoprotein Receptor; CD36 Antigen like 1; CD36L1; CLA 1; CLA1;SR BI; SRB1; SRBI; Scavenger Receptor BI; CD36 AND LIMPII ANALOGOUS 1; CD36 Antigen like 1; CD36L1; CLA 1; CLA1; Collagen type I receptor; MGC138242; SCARB1; Scavebger Receptor Class B Member 1; Scavenger Receptor Class B Type 1; SR BI; SRB1; SRBI; Thrombospondin receptor like 1; High density lipoprotein receptor SR-BI.  
研究領(lǐng)域 免疫學(xué)  生長因子和激素  細(xì)胞膜受體  糖蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Mouse (predicted: Rat)
產(chǎn)品應(yīng)用 WB=1:500-2000,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 61kDa
細(xì)胞定位 細(xì)胞漿 細(xì)胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from mouse SCARB1/Scavenger Receptor BI : 411-509/509 <Cytoplasmic>
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 High density lipoproteins (HDLs) play a critical role in cholesterol metabolism and their plasma concentrations are inversely correlated with risk for atherosclerosis. The SR-BI (Scavenger Receptor BI) protein binds HDLs and mediates selective uptake of HDL cholesteryl ester. SR-BI binds HDL with high affinity, is expressed primarily in liver and nonplacental steroidgenic tissues, and mediates selective cholesterol uptake by a distinct mechanism. In mice, it seems that SR-BI plays a key role in determining the levels of plasma lipoprotein cholesterol and the accumulation of cholesterol stores in the adrenal gland. Scavenging Receptor SR-BI plays a critical role in HCV attachment and/or cell entry by interacting with HCV E1/E2 glycoproteins heterodimer.

Function:
Receptor for different ligands such as phospholipids, cholesterol ester, lipoproteins, phosphatidylserine and apoptotic cells. Probable receptor for HDL, located in particular region of the plasma membrane, called caveolae. Facilitates the flux of free and esterified cholesterol between the cell surface and extracellular donors and acceptors, such as HDL and to a lesser extent, apoB-containing lipoproteins and modified lipoproteins. Probably involved in the phagocytosis of apoptotic cells, via its phosphatidylserine binding activity. Receptor for hepatitis C virus glycoprotein E2. Binding between SCARB1 and E2 was found to be independent of the genotype of the viral isolate. Plays an important role in the uptake of HDL cholesteryl ester.

Subunit:
Plays a critical role in HCV attachment and/or cell entry by interacting with HCV E1/E2 glycoproteins heterodimer. The C-terminal region binds to PDZK1.

Subcellular Location:
Cell membrane; Multi-pass membrane protein. Membrane, caveola; Multi-pass membrane protein. Note=Predominantly localized to cholesterol and sphingomyelin-enriched domains within the plasma membrane, called caveolae.

Tissue Specificity:
Widely expressed.

Post-translational modifications:
N-glycosylated.
The six cysteines of the extracellular domain are all involved in intramolecular disulfide bonds.

Similarity:
Belongs to the CD36 family.

SWISS:
Q61009

Gene ID:
20778

Database links:

Entrez Gene: 949 Human

Entrez Gene: 20778 Mouse

Entrez Gene: 25073 Rat

Omim: 601040 Human

SwissProt: Q8WTV0 Human

SwissProt: Q61009 Mouse

SwissProt: P97943 Rat

Unigene: 520348 Human

Unigene: 282242 Mouse

Unigene: 88169 Rat



組織細(xì)胞中存在多種高密度脂蛋白受體或高密度脂蛋白結(jié)合蛋白,這些受體蛋白的組成、結(jié)構(gòu)及一般特征各不相同;高密度脂蛋白受體在脂質(zhì)代謝中發(fā)揮著重要的作用。
產(chǎn)品圖片
Sample: Ovary (Mouse) Lysate at 40 ug Primary: Anti- SCARB1 (bs-23977R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 61 kD Observed band size: 57 kD
版權(quán)所有 2004-2026 www.www.p2b3.cn 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
界首市| 乌拉特前旗| 将乐县| 阜南县| 邹城市| 天长市| 祁阳县| 眉山市| 百色市| 云林县| 赤水市| 宜章县| 和硕县| 隆回县| 镇坪县| 武安市| 喜德县| 鄂伦春自治旗| 德兴市| 贵南县| 田东县| 沙河市| 斗六市| 新闻| 邵东县| 大理市| 锦州市| 昆山市| 建德市| 扶风县| 葫芦岛市| 土默特左旗| 海原县| 东海县| 兴国县| 木兰县| 孙吴县| 阳城县| 五指山市| 清镇市| 日土县|