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Rabbit Anti-IGFBP3  antibody (bs-22862R)  
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產(chǎn)品編號 bs-22862R
英文名稱 Rabbit Anti-IGFBP3  antibody
中文名稱 胰島素樣生長因子結(jié)合蛋白3抗體
別    名 IBP3_HUMAN; Insulin-like growth factor-binding protein 3; IBP3; IBP-3; IGF-binding protein 3; IGFBP-3; IBP3; BP-53;   
研究領域 腫瘤  細胞生物  免疫學  生長因子和激素  糖尿病  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Mouse,Rat (predicted: Human,Pig,Sheep,Cow,Horse)
產(chǎn)品應用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 32kDa
細胞定位 分泌型蛋白 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human IGFBP3: 131-231/292 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 This gene is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein forms a ternary complex with insulin-like growth factor acid-labile subunit (IGFALS) and either insulin-like growth factor (IGF) I or II. In this form, it circulates in the plasma, prolonging the half-life of IGFs and altering their interaction with cell surface receptors. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]

Subcellular Location:
Secreted.

Tissue Specificity:
Expressed by most tissues. Present in plasma.

Post-translational modifications:
Phosphorylation sites are present in the extracelllular medium.

Similarity:
Contains 1 IGFBP N-terminal domain.
Contains 1 thyroglobulin type-1 domain.

SWISS:
P17936

Gene ID:
3486

Database links:

Entrez Gene: 3486 Human

Entrez Gene: 16009 Mouse

Entrez Gene: 24484 Rat

SwissProt: P17936 Human

SwissProt: P47878 Mouse

SwissProt: P15473 Rat



產(chǎn)品圖片
Sample: Lane 1: Mouse Liver tissue lysates Lane 2: Rat Liver tissue lysates Primary: Anti-IGFBP3 (bs-22862R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 32 kDa Observed band size: 46 kDa
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