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Rabbit Anti-BBC3/PUMA, BF750 conjugated antibody (bs-1573R-BF750)  
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說明書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-1573R-BF750
英文名稱 Rabbit Anti-BBC3/PUMA, BF750 conjugated antibody
中文名稱 BF750標記的p53正向細胞凋亡調控因子抗體
別    名 PUMA; bcl-2 binding component 3; BBC 3; BBC3; BCL 2 binding component 3; BCL2 binding component 3; JFY 1; JFY1; p53 up regulated modulator of apoptosis; p53 Upregulated Modulator of Apoptosis; PUMA alpha; PUMA/JFY1; BBC3_RAT.  
研究領域 腫瘤  細胞生物  免疫學  細胞凋亡  線粒體  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應
產(chǎn)品應用
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 21kDa
細胞定位 細胞漿 線粒體
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human BBC3: 131-180/193 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 This gene encodes a member of the BCL-2 family of proteins. This family member belongs to the BH3-only pro-apoptotic subclass. The protein cooperates with direct activator proteins to induce mitochondrial outer membrane permeabilization and apoptosis. It can bind to anti-apoptotic Bcl-2 family members to induce mitochondrial dysfunction and caspase activation. Because of its pro-apoptotic role, this gene is a potential drug target for cancer therapy and for tissue injury. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2011]

SWISS:
Q96PG8

Gene ID:
27113

Database links:

Entrez Gene: 27113 Human

Entrez Gene: 170770 Mouse

Entrez Gene: 317673 Rat

Omim: 605854 Human

SwissProt: Q9BXH1 Human

SwissProt: Q99ML1 Mouse

SwissProt: Q80ZG6 Rat

Unigene: 467020 Human

Unigene: 7660 Mouse

Unigene: 25176 Rat



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