產(chǎn)品編號 | bs-1305R-Gold |
英文名稱1 | Rabbit Anti-CCR7/Gold Conjugated antibody |
中文名稱 | 膠體金標記的細胞表面趨化因子受體7抗體 |
別 名 | BLR 2; BLR2; C C chemokine receptor type 7; C C CKR 7; CC chemokine receptor 7; CC chemokine receptor type 7; CC CKR 7; CCCKR7; CCR 7; CD 197; CD197; CD197 antigen; CDW197; Chemokine C C motif receptor 7; Chemokine C C receptor 7; Chemokine receptor 7-like protein; EBI 1; EBI1; Ebi1h; EBV Induced G Protein Coupled Receptor 1; Epstein Barr virus induced G protein coupled receptor; Epstein Barr virus induced gene 1; EVI 1; EVI1; Lymphocyte Specific G Protein Coupled Peptide Receptor; MGC108519; MIP 3 beta receptor; MIP3 Beta Receptor. |
規(guī)格價格 | 100ul/2980元 購買 大包裝/詢價 |
說 明 書 | 100ul(10nm 15nm 35nm) |
研究領域 | 細胞生物 免疫學 細胞凋亡 細胞膜受體 |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應 | Mouse, (predicted: Human, Rat, Dog, ) |
產(chǎn)品應用 | IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 42kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | 0.4mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human CCR7 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲 存 液 | 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300. |
保存條件 | Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles. |
產(chǎn)品介紹 |
background: The protein encoded by this gene is a member of the G protein-coupled receptor family. This receptor was identified as a gene induced by the Epstein-Barr virus (EBV), and is thought to be a mediator of EBV effects on B lymphocytes. This receptor is expressed in various lymphoid tissues and activates B and T lymphocytes. It has been shown to control the migration of memory T cells to inflamed tissues, as well as stimulate dendritic cell maturation. The chemokine (C-C motif) ligand 19 (CCL19/ECL) has been reported to be a specific ligand of this receptor. [provided by RefSeq, Jul 2008] Function: Receptor for the MIP-3-beta chemokine. Probable mediator of EBV effects on B-lymphocytes or of normal lymphocyte functions. Subcellular Location: Cell membrane; Multi-pass membrane protein. Tissue Specificity: Expressed in various lymphoid tissues and activated B- and T-lymphocytes, strongly up-regulated in B-cells infected with Epstein-Barr virus and T-cells infected with herpesvirus 6 or 7. Similarity: Belongs to the G-protein coupled receptor 1 family. Database links: Entrez Gene: 1236 Human Entrez Gene: 12775 Mouse Omim: 600242 Human SwissProt: P32248 Human SwissProt: P47774 Mouse Unigene: 370036 Human Unigene: 2932 Mouse Unigene: 229736 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 趨化因子是當今細胞因子研究領域的熱點之一,它參與多種免疫及炎癥反應,在感染、腫瘤的生長與轉移、組織修復及創(chuàng)傷愈合等病理生理過程中發(fā)揮重要作用.CCR7在腫瘤的生長與轉移方面起到一定的作用. |
1、抗體溶解方法 | |
2、抗體修復方式 | |
3、常用試劑的配制 | |
4、免疫組化操作步驟 | |
5、免疫組化問題解答 | |
6、Western Blotting 操作步驟 | |
7、Western Blotting 問題解答 | |
8、關于肽鏈的設計 | |
9、多肽的溶解與保存 | |
10、酶標抗體效價測定程序 | |