產(chǎn)品編號(hào) | bs-1524R-Gold |
英文名稱1 | Rabbit Anti-GlyR alpha 1 + 2 + 3/Gold Conjugated antibody |
中文名稱 | 膠體金標(biāo)記的甘氨酸受體alpha 1/2/3型抗體 |
別 名 | glycine receptor alpha 1; glycine receptor alpha 2; glycine receptor alpha 3; GLRA1; GLRA2; Glycine receptor 48 kDa subunit; Glycine receptor alpha 2; Glycine receptor subunit alpha 3; Glycine receptor subunit alpha 2; Glycine receptor, alpha 1 subunit; Glycine receptor, alpha 2 subunit; MGC138878; MGC138879; STHE; alpha 1 Glycine Receptor; GLRA1; GLRA1_HUMAN; Glycine receptor 48 kDa subunit; Glycine receptor alpha 1; Glycine receptor strychnine-binding subunit; Glycine receptor subunit alpha-1; Glycine receptor, alpha 1 subunit; HKPX1; STHE; GLR; Glra2; GLRA2_HUMAN; Glycine receptor alpha 2 polypeptide; Glycine receptor alpha 2 subunit; Glycine receptor subunit alpha 2; Glycine receptor subunit alpha-2; Gycine receptor alpha 2. |
規(guī)格價(jià)格 | 100ul/2980元 購(gòu)買(mǎi) 大包裝/詢價(jià) |
說(shuō) 明 書(shū) | 100ul(10nm 15nm 35nm) |
研究領(lǐng)域 | 免疫學(xué) 神經(jīng)生物學(xué) 通道蛋白 細(xì)胞膜受體 G蛋白偶聯(lián)受體 G蛋白信號(hào) |
抗體來(lái)源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | Mouse, Rat, (predicted: Human, Chicken, Dog, Pig, Cow, Horse, Rabbit, ) |
產(chǎn)品應(yīng)用 | IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 49kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | 0.4mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human GlyR alpha 1 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲(chǔ) 存 液 | 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300. |
保存條件 | Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles. |
產(chǎn)品介紹 |
background: Glycine receptors are members of the ligand-gated ion channel superfamily, which mediate fast inhibitory neurotransmission. The receptors are pentameric membrane proteins which form chloride channels. Binding of glycine to its receptor produces an increase in chloride conductance and membrane hyperpolarisation. Four genes encoding glycine receptor alpha subunits have been identified, together with a single beta polypeptide. Each subunit consists of a large extracellular N-terminal region, four transmembrane domains, and a large cytoplasmic domain. Subcellular Location: Cell Membrane Database links: Entrez Gene: 2741 Human Entrez Gene: 14654 Mouse Omim: 138491 Human SwissProt: P23415 Human SwissProt: Q64018 Mouse Unigene: 121490 Human Unigene: 89320 Mouse Unigene: 10109 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 甘氨酸受體alpha 1是中樞神經(jīng)系統(tǒng)中的重要抑制性離子通道受體,是哺乳類中樞神經(jīng)系統(tǒng)中神經(jīng)遞質(zhì)受體蛋白,屬于配體門(mén)控離子通道超家族成員. |