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Rabbit Anti-CD30/Gold Conjugated antibody (bs-4778R-Gold)
訂購熱線:400-901-9800
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訂購QQ:  400-901-9800
技術支持:techsupport@www.p2b3.cn
說 明 書: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢價
產品編號 bs-4778R-Gold
英文名稱1 Rabbit Anti-CD30/Gold Conjugated antibody
中文名稱 膠體金標記的CD30抗體
別    名 CD 30; CD30; CD30 antigen; CD30L receptor; Cytokine receptor CD30; D1S166E; KI 1; Ki 1 antigen; Ki-1 antigen; KI1; Lymphocyte activation antigen CD30; TNFRSF 8; TNFRSF8; TNFRSF8; TNR8_MOUSE; Tumor Necrosis Factor Receptor Superfamily Member 8; Tumor Necrosis Factor Receptor Superfamily Member 8.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul(10nm  15nm  35nm
研究領域 腫瘤  細胞生物  細胞類型標志物  腫瘤細胞生物標志物  細胞因子  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Rat,  (predicted: Mouse, )
產品應用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 51kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from mouse TNFRSF
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產品介紹 background:
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB. This receptor is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]

Function:
Receptor for TNFSF8/CD30L. May play a role in the regulation of cellular growth and transformation of activated lymphoblasts. Regulates gene expression through activation of NF-kappa-B.

Subunit:
Interacts with TRAF1, TRAF2, TRAF3 and TRAF5.

Subcellular Location:
Membrane; Single-pass type I membrane protein (Probable).

Tissue Specificity:
Detected in thymus and in activated splenocytes.

Similarity:
Contains 3 TNFR-Cys repeats.

Database links:

Entrez Gene: 943 Human

Entrez Gene: 21941 Mouse

Omim: 153243 Human

SwissProt: P28908 Human

Unigene: 1314 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

CD30是一種單鏈糖蛋白,標記活化T和B淋巴細胞,R-S細胞和部分淋巴濾泡間區(qū)免疫母細胞。CD30是霍奇金淋巴瘤的一個特異性標記,也是大細胞間變型淋巴瘤的診斷型標志。
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