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Rabbit Anti-G1switch 2/Gold Conjugated antibody (bs-8656R-Gold)
訂購熱線:400-901-9800
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訂購QQ:  400-901-9800
技術支持:techsupport@www.p2b3.cn
說 明 書: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢價
產品編號 bs-8656R-Gold
英文名稱1 Rabbit Anti-G1switch 2/Gold Conjugated antibody
中文名稱 膠體金標記的G0/G1期開關調節(jié)蛋白2抗體
別    名 G0/G1 switch regulatory protein 2; G0/G1switch 2; G0s2; G0S2_HUMAN; OTTHUMP00000034644; Putative lymphocyte G0/G1 switch protein 2; RP1 28O10.2.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul(10nm  15nm  35nm
研究領域 腫瘤  細胞生物  細胞周期蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Horse, )
產品應用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 11kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human G0/G1 switch protein 2 (1-50aa)
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產品介紹 background:
G0S2 is a 103 amino acid novel target of peroxisome proliferator-activated receptors (PPARs) and regulator of latent HIV. G0S2 may be involved in adipocyte differentiation and its expression is essential for committing cells to enter the G1 phase of the cell cycle. G0S2 contains a CpG-rich island and multiple sites for potential phosphorylation by casein kinase II and protein kinase C. The gene encoding G0S2 maps to human chromosome 1, which is the largest human chromosome. Chromosome 1 spans about 260 million base pairs and makes up 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma.

Function:
Potential oncogene and regulator of latent HIV.

Subunit:
Directly interacts with BCL2; this interaction prevents the formation of the anti-apoptotic BAX-BCL2 complex.

Subcellular Location:
Mitochondrion.

Tissue Specificity:
Widely expressed with highest levels in peripheral blood, skeletal muscle and heart, followed by kidney and liver.

Database links:
UniProtKB/Swiss-Prot: P27469.

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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