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Rabbit Anti-CD99/AP Conjugated antibody (bs-2523R-AP)
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說(shuō) 明 書(shū): 100ul  
100ul/2980.00元
大包裝/詢(xún)價(jià)
產(chǎn)品編號(hào) bs-2523R-AP
英文名稱(chēng)1 Rabbit Anti-CD99/AP Conjugated antibody
中文名稱(chēng) 堿性磷酸酶(AP)標(biāo)記的CD99抗體
別    名 T-cell surface glycoprotein E; T cell surface glycoprotein E2 precursor; 12E7; Antigen identified by monoclonal 12E7 Y homolog; Antigen identified by monoclonal antibodies 12E7 F21 and O13; CD 99; CD99 antigen; CD99 molecule; CD99X; E2 antigen; Ewing Sarcoma; MIC 2; MIC 2X; MIC 2Y; MIC2; MIC2X; MIC2Y; Monoclonal antibody 12E7; MSK5X; Protein MIC2; Surface antigen MIC2.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買(mǎi)        大包裝/詢(xún)價(jià)
說(shuō) 明 書(shū) 100ul  
研究領(lǐng)域 腫瘤  細(xì)胞生物  免疫學(xué)  細(xì)胞表面分子  糖蛋白  細(xì)胞類(lèi)型標(biāo)志物  t-淋巴細(xì)胞  
抗體來(lái)源 Rabbit
克隆類(lèi)型 Polyclonal
交叉反應(yīng) Mouse,  (predicted: Rat, )
產(chǎn)品應(yīng)用 WB=1:50-200 IHC-P=1:50-200 IHC-F=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 16kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from mouse CD99
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
The protein encoded by this gene is a cell surface glycoprotein involved in leukocyte migration, T-cell adhesion, ganglioside GM1 and transmembrane protein transport, and T-cell death by a caspase-independent pathway. In addition, the encoded protein may have the ability to rearrange the actin cytoskeleton and may also act as an oncosuppressor in osteosarcoma. Cyclophilin A binds to CD99 and may act as a signaling regulator of CD99. This gene is found in the pseudoautosomal region of chromosomes X and Y and escapes X-chromosome inactivation. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

Function:
Involved in T-cell adhesion processes. Plays a role in a late step of leukocyte extravasation helping leukocytes to overcome the endothelial basement membrane. Acts at the same site as, but independently of, PECAM1.

Subunit:
Homodimer. Interacts with PILRB.

Subcellular Location:
Membrane; Single-pass type I membrane protein.

Tissue Specificity:
Natural killer cells.

Similarity:
Belongs to the CD99 family.

Database links:

Entrez Gene: 4267 Human

Entrez Gene: 673094 Mouse

Omim: 313470 Human

SwissProt: P14209 Human

SwissProt: Q8VCN6 Mouse

Unigene: 653349 Human

Unigene: 423040 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

CD99(P30/32MIC2)是一種跨膜蛋白,為MIC2基因產(chǎn)物。分布于淋巴細(xì)胞、胸腺皮質(zhì)細(xì)胞、卵巢的顆粒細(xì)胞、胰島細(xì)胞和睪丸支持細(xì)胞。
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