產(chǎn)品編號(hào) | bsm-2059M-Gold |
英文名稱1 | Mouse Anti-Metronidazole(1C2)/Gold Conjugated antibody |
中文名稱 | 膠體金標(biāo)記的甲硝唑單克隆抗體 |
別 名 | 2-Methyl-5-nitroimidazole-1-ethanol |
規(guī)格價(jià)格 | 100ul/2980元 購買 大包裝/詢價(jià) |
說 明 書 | 100ul(10nm 15nm 35nm) |
產(chǎn)品類型 | 小分子抗體 |
研究領(lǐng)域 | 免疫學(xué) 藥物及化合物 |
抗體來源 | Mouse |
克隆類型 | Monoclonal |
克 隆 號(hào) | 1C2 |
交叉反應(yīng) | |
產(chǎn)品應(yīng)用 | IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 0.17115kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | 0.4mg/ml |
免 疫 原 | KLH conjugated with Metronidazole |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲(chǔ) 存 液 | 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300. |
保存條件 | Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles. |
產(chǎn)品介紹 |
background: Metronidazole is a nitroimidazole antibiotic medication used particularly for anaerobic bacteria and protozoa. Metronidazole is an antibiotic, amebicide, and antiprotozoal.Metronidazole, taken up by diffusion, is selectively absorbed by anaerobic bacteria and sensitive protozoa. Once taken up by anaerobes, it is non-enzymatically reduced by reacting with reduced ferredoxin, which is generated by pyruvate oxido-reductase. Many of the reduced nitroso intermediates will form sulfinamides and thioether linkages with cysteine-bearing enzymes, thereby deactivating these critical enzymes. As many as 150 separate enzymes are affected.In addition or alternatively, the metronidazole metabolites are taken up into bacterial DNA, and form unstable molecules. This function only occurs when metronidazole is partially reduced, and because this reduction usually happens only in anaerobic cells, it has relatively little effect upon human cells or aerobic bacteria. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |