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Rabbit Anti-GPR15/BF488 Conjugated antibody (bs-3699R-BF488)
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說(shuō) 明 書(shū): 100ul  
100ul/2980.00元
大包裝/詢(xún)價(jià)

產(chǎn)品編號(hào) bs-3699R-BF488
英文名稱(chēng)1 Rabbit Anti-GPR15/BF488 Conjugated antibody
中文名稱(chēng) BF488標(biāo)記的G蛋白偶聯(lián)受體15抗體
別    名 GPCR GPR15; BOB; G protein coupled receptor 15; G protein coupled receptor GPR15; GPR15_HUMAN; G-protein coupled receptor 15; Brother of Bonzo.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買(mǎi)        大包裝/詢(xún)價(jià)
說(shuō) 明 書(shū) 100ul  
研究領(lǐng)域 腫瘤  細(xì)胞生物  免疫學(xué)  信號(hào)轉(zhuǎn)導(dǎo)  G蛋白偶聯(lián)受體  細(xì)胞表面分子  G蛋白信號(hào)  
抗體來(lái)源 Rabbit
克隆類(lèi)型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat,  (predicted: Dog, Horse, Rabbit, )
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 40kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human GPR15
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
This gene encodes a G protein-coupled receptor that acts as a chemokine receptor for human immunodeficiency virus type 1 and 2. The encoded protein localizes to the cell membrane. [provided by RefSeq, Nov 2012]

Function:
Probable chemokine receptor. Alternative coreceptor with CD4 for HIV-1 infection.

Subcellular Location:
Cell membrane; Multi-pass membrane protein.

Similarity:
Belongs to the G-protein coupled receptor 1 family.

Database links:

Entrez Gene: 2838 Human

Entrez Gene: 71223 Mouse

Entrez Gene: 288181 Rat

Omim: 601166 Human

SwissProt: P49685 Human

SwissProt: Q0VDU3 Mouse

Unigene: 563128 Human

Unigene: 359970 Mouse

Unigene: 426544 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

G蛋白偶聯(lián)受體是一種細(xì)胞表面受體,能將細(xì)胞外的分子信號(hào)傳遞至細(xì)胞內(nèi)激起細(xì)胞反應(yīng),對(duì)多種細(xì)胞行起調(diào)控作用。G蛋白偶聯(lián)受體(GPCR)參與了機(jī)體內(nèi)多種生理過(guò)程的調(diào)節(jié),是目前治療多種人類(lèi)疾病包括代謝性疾病的藥物靶點(diǎn)。
產(chǎn)品圖片
Paraformaldehyde-fixed, paraffin embedded (Human brain glioma); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Incubation: Anti-GPR15 Antibody, conjugated (bs-3699R-BF488) 1:400, 1.5 hours at 37°C; DAPI (5ug/ml, blue, C-0033) was used to stain the cell nuclei.
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