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Rabbit Anti-ICAD/Gold Conjugated antibody (bs-0214R-Gold)
訂購熱線:400-901-9800
訂購郵箱:sales@www.p2b3.cn
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@www.p2b3.cn
說 明 書: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-0214R-Gold
英文名稱1 Rabbit Anti-ICAD/Gold Conjugated antibody
中文名稱 膠體金標記的Caspase激活的脫氧核糖核酸酶抑制劑抗體
別    名 DFF-45 Beta; ICAD; ICAD L; ICAD S; Caspase activated deoxyribonuclease inhibitor short form; DFF 1; DFF 45; DFF-45; DFF alpha; DFF1; DFF35; DFF45; DFFA; Dffa DNA fragmentation factor, alpha subunit; DNA fragmentation factor 45 kDa subunit; DNA Fragmentation Factor Alpha Subunit; DNA fragmentation factor subunit alpha; DNA fragmentation factor, 45 kD, alpha subunit; DNA fragmentation factor, 45kDa, alpha polypeptide (DFFA), transcript variant 1; A330085O09Rik; DNA fragmentation factor, 45kDa, alpha polypeptide; DNA fragmentation factor, alpha subunit; H13; Inhibitor of CAD; DFFA_HUMAN; Inhibitor of CAD; Inhibitor of Caspase Activated DNase; MGC143066; OTTHUMP00000001903; OTTHUMP00000001904; RP23 121D17.3;Inhibitor of Caspase Activated DNase.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul(10nm  15nm  35nm
研究領(lǐng)域 細胞生物  免疫學  染色質(zhì)和核信號  細胞凋亡  新陳代謝  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human, Mouse, Rat, 
產(chǎn)品應用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 36kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human ICAD
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產(chǎn)品介紹 background:
Caspase-activated deoxyribonuclease(CAD) also designated DNA fragmentation factor 45 kDa subunit (DFF-45)and Caspase-activated DNase. CAD is a nuclease that induces DNA fragmentation and chromatin condensation during apoptosis. Degrades naked DNA and induces apoptotic morphology. ICAD (DNA fragmentation factor alpha subunit) (DNA fragmentation factor 45 kDa subunit) (DFF-45) (Inhibitor of CAD) is inhibitor of the caspase-activated DNase (DFF44).

Function:
Inhibitor of the caspase-activated DNase (DFF40).

Subunit:
Heterodimer of DFFA and DFFB.

Subcellular Location:
Cytoplasm.

Post-translational modifications:
Caspase-3 cleaves DFF45 at 2 sites to generate an active factor.

Similarity:
Contains 1 CIDE-N domain.

Database links:

Entrez Gene: 1676 Human

Omim: 601882 Human

SwissProt: O00273 Human

Unigene: 484782 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

ICAD 是在細胞凋亡期誘導DNA分裂和染色體固縮的一種核酶,降解裸露的DNA 并誘導形態(tài)學變化。
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