| 產(chǎn)品編號 | bs-12216R-BF350 |
| 英文名稱1 | Rabbit Anti-ZNF3/BF350 Conjugated antibody |
| 中文名稱 | BF350標(biāo)記的鋅指蛋白3抗體 |
| 別 名 | A8 51; C2 H2 type zinc finger protein; FLJ20216; HF.12; HZF3.1; KOX25; PP838; Zfp113; Zinc finger protein 3 (A8 51); Zinc finger protein 3; Zinc finger protein HF.12; Zinc finger protein KOX25; ZNF3_HUMAN. |
| 規(guī)格價格 | 100ul/2980元 購買 大包裝/詢價 |
| 說 明 書 | 100ul |
| 研究領(lǐng)域 | 轉(zhuǎn)錄調(diào)節(jié)因子 鋅指蛋白 表觀遺傳學(xué) |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Sheep, ) |
| 產(chǎn)品應(yīng)用 | ICC=1:50-200 IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 51kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from Human ZNF3 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol |
| 保存條件 | Store at -20 癈 for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20癈. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 癈. |
| 產(chǎn)品介紹 |
background: Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Kruppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. ZNF3, also known as KOX25, is a zinc finger protein belonging to the Kruppel C(2)H(2)-type zinc finger protein family. It localizes to the nucleus and is involved in cell differentiation and proliferation. ZNF3 is a 446 amino acid long protein that contains eight C(2)H(2)-type zinc fingers and one KRAB domain. ZNF3 is located in a cluster of KOX zinc-finger genes found on chromosome 10. Function: A zinc finger is a protein domain that can bind to DNA. A zinc finger consists of two antiparallel ?sheets, and an alpha helix. The structure of each individual finger is highly conserved and consists of about 30 amino acid residues, constructed as a 哌alpha fold and held together by the zinc ion. The alpha helix occurs at the C terminal part of the finger, while the ?sheet occurs at the N terminal part. Subcellular Location: Nuclear Similarity: Belongs to the krueppel C2H2-type zinc-finger protein family. Contains 8 C2H2-type zinc fingers. Contains 1 KRAB domain. Database links: Entrez Gene: 7551 Human Omim: 194510 Human SwissProt: P17036 Human Unigene: 435302 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
