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Rabbit Anti-EML3/Gold Conjugated antibody (bs-9731R-Gold)
訂購熱線:400-901-9800
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訂購QQ:  400-901-9800
技術支持:techsupport@www.p2b3.cn
說 明 書: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-9731R-Gold
英文名稱1 Rabbit Anti-EML3/Gold Conjugated antibody
中文名稱 膠體金標記的微管相關蛋白樣蛋白3抗體
別    名 Echinoderm microtubule associated protein like 3; ELP 95; EMAP 3; EMAP3; EMAP-3; EML 3; EML3; EML-3; FLJ 35827; MGC 111422; EMAL3_HUMAN.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul(10nm  15nm  35nm
研究領域 細胞生物  細胞周期蛋白  細胞分化  細胞骨架  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Rabbit, )
產(chǎn)品應用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 95kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from hu EML3
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產(chǎn)品介紹 background:
At the onset of mitosis, assembly of the mitotic spindle requires a global change in the activity of microtubule-binding proteins. EML3 (Echinoderm microtubule-associated protein-like 3) is a 896 amino acid protein that likely modifies microtubule dynamics by making them longer. Through colocalization with spindle microtubules during mitosis, EML3 plays a role in correct metaphase chromosome alignment. EML3 contains a nuclear localization signal and a microtubule-binding domain. The gene encoding EML3 maps to human chromosome 11, which houses over 1,400 genes and comprises nearly 4% of the human genome. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are associated with defects in genes that maps to chromosome 11.

Function:
May modify the assembly dynamics of microtubules, such that microtubules are slightly longer, but more dynamic (By similarity).

Subcellular Location:
Cytoplasmic

Similarity:
Belongs to the WD repeat EMAP family.
Contains 9 WD repeats.

Database links:

Entrez Gene: 256364 Human

Entrez Gene: 225898 Mouse

Entrez Gene: 293723 Rat

SwissProt: Q32P44 Human

SwissProt: Q8VC03 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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