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Rabbit Anti-APOH/RBITC Conjugated antibody (bs-1570R-RBITC)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-1570R-RBITC
英文名稱1 Rabbit Anti-APOH/RBITC Conjugated antibody
中文名稱 羅丹明(RBITC)標(biāo)記的載脂蛋白H抗體
別    名 Apolipoprotein H; Activated protein C binding protein; APC inhibitor; APOH; B2G1; beta 2 glycoprotein I; beta 2 glycoprotein I precursor; BG; OTTMUSP00000003033; APOH_HUMAN.  
規(guī)格價(jià)格 100ul/2980元 購買        大包裝/詢價(jià)
說 明 書 100ul  
研究領(lǐng)域 心血管  免疫學(xué)  合成與降解  糖蛋白  脂蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human,  (predicted: Mouse, Rat, Dog, Cow, Horse, Rabbit, )
產(chǎn)品應(yīng)用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 36kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human ApoH
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
Apolipoprotein H is expressed by placental trophoblast cells at high levels. Although the normal physiological role is not known, the protein appears to act as a co-factor for the binding of autoantibodies to phospholipids to trophoblasts, which is a process involved in the pathogenesis of recurrent miscarriage.

Function:
Binds to various kinds of negatively charged substances such as heparin, phospholipids, and dextran sulfate. May prevent activation of the intrinsic blood coagulation cascade by binding to phospholipids on the surface of damaged cells.

Subcellular Location:
Secreted.

Tissue Specificity:
Expressed by the liver and secreted in plasma.

Post-translational modifications:
N- and O-glycosylated. PubMed:6587378 also reports glycosylation on 'Asn-188' for their allele.

Similarity:
Contains 4 Sushi (CCP/SCR) domains.

Database links:

Entrez Gene: 350 Human

Entrez Gene: 287774 Rat

Omim: 138700 Human

SwissProt: P02749 Human

SwissProt: P26644 Rat

Unigene: 445358 Human

Unigene: 1824 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

載脂蛋白H(apolipoprotein D,apoH)又稱為β2糖蛋白Ⅰ(β2-glycoprotein,β2-GI),是最初是在人血漿的高密度脂蛋白中被分離出來的。apoH在結(jié)構(gòu)上與其他類型的載脂蛋白存在很大的差異,被歸入脂肪促成素家族。
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