mm1313亚洲精品,欧美俄罗斯40老熟妇,欧美日韩在线观看视频在线,亚洲欧美国产激情综合在线

掃碼關(guān)注公眾號(hào)           掃碼咨詢(xún)技術(shù)支持           掃碼咨詢(xún)技術(shù)服務(wù)
  
客服熱線(xiàn):400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  人才招聘  關(guān)于我們  聯(lián)系我們
亚洲精品~无码抽插,国产女王电影av在线,亚洲AV无码乱码情品国产
Rabbit Anti-SMAD9/PE Conjugated antibody (bs-4253R-PE)
訂購(gòu)熱線(xiàn):400-901-9800
訂購(gòu)郵箱:sales@www.p2b3.cn
訂購(gòu)QQ:  400-901-9800
技術(shù)支持:techsupport@www.p2b3.cn
說(shuō) 明 書(shū): 100ul  
100ul/2980.00元
大包裝/詢(xún)價(jià)
產(chǎn)品編號(hào) bs-4253R-PE
英文名稱(chēng)1 Rabbit Anti-SMAD9/PE Conjugated antibody
中文名稱(chēng) PE標(biāo)記的SMAD家族9抗體
別    名 AI528653 ; BSP 1 ; BSP1 ; DKFZp781C1895 ; DKFZp781O1323 ; Dwarfin A ; Dwf A ; DwfA ; Dwfc ; hSMAD1 ; hSmad5 ; JV 41 ; JV4 1 ; JV41 ; JV5 1 ; MAD (mothers against decapentaplegic, Drosophila) homolog 1 ; MAD (mothers against decapentaplegic, Drosophila) homolog 9 ; MAD homolog 1 ; MAD homolog 9 ; MAD homolog1 (mothers against decapentaplegic, Drosophila) ; Mad related protein 1 ; MAD, mothers against decapentaplegic homolog 9 ; MADH 1 ; Madh1 ; MADH5 ; MADH6 ; MADH9 ; Madr 1 ; MADR1 ; Mlp1 ; Mothers against decapentaplegic, drosophila, homolog of, 9 ; Mothers against DPP homolog 1 ; Mothers against DPP homolog 9 ; MusMLP ; OTTHUMP00000178565 ; OTTMUSP00000022970 ; OTTMUSP00000022971 ; OTTMUSP00000022972 ; OTTMUSP0000002324 ; OTTMUSP00000023428 ; Sma and Mad related protein 1 ; Sma- and Mad-related protein 1 ; SMAD ; SMAD family member 5 ; SMAD mothers against DPP homolog 1 Drosophila ; SMAD8 ; SMAD8A ; SMAD8B ; Spinal muscular atrophy distal with upper limb predominance ; TGF beta signaling protein 1 ; Transforming growth factor beta signaling protein 1 ; Transforming growth factor-beta signaling protein 1.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買(mǎi)        大包裝/詢(xún)價(jià)
說(shuō) 明 書(shū) 100ul  
研究領(lǐng)域 腫瘤  免疫學(xué)  染色質(zhì)和核信號(hào)  信號(hào)轉(zhuǎn)導(dǎo)  干細(xì)胞  生長(zhǎng)因子和激素  轉(zhuǎn)錄調(diào)節(jié)因子  
抗體來(lái)源 Rabbit
克隆類(lèi)型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, )
產(chǎn)品應(yīng)用 Flow-Cyt=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 52kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human SMAD9
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
SMAD9 is a member of the MAD-related family of molecules. MAD-related proteins are a recently identified family of intracellular proteins that are thought to be essential components in the signaling pathways of the serine/threonine kinase receptors of the transforming growth factor beta superfamily.

Function:
Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD9 is a receptor-regulated SMAD (R-SMAD).

Subunit:
Interaction with the co-SMAD SMAD4. Interacts with PEBP2-alpha subunit.

Subcellular Location:
Cytoplasm (By similarity). Nucleus (By similarity). Note=In the cytoplasm in the absence of ligand. Migration to the nucleus when complexed with SMAD4 (By similarity).

Tissue Specificity:
Expressed in heart, brain, placenta, lung, skeletal muscle, prostate, testis, ovary and small intestine. Also expressed in fetal brain, lung and kidney.

Post-translational modifications:
Phosphorylated on serine by BMP (bone morphogenetic proteins) type 1 receptor kinase.

DISEASE:
Defects in SMAD9 may be a cause of primary pulmonary hypertension (PPH1) [MIM:178600]. A rare disorder characterized by plexiform lesions of proliferating endothelial cells in pulmonary arterioles. The lesions lead to elevated pulmonary arterial pression, right ventricular failure, and death. The disease can occur from infancy throughout life and it has a mean age at onset of 36 years. Penetrance is reduced. Although familial PPH1 is rare, cases secondary to known etiologies are more common and include those associated with the appetite-suppressant drugs.

Similarity:
Belongs to the dwarfin/SMAD family.
Contains 1 MH1 (MAD homology 1) domain.
Contains 1 MH2 (MAD homology 2) domain.

Database links:

Entrez Gene: 4093 Human

Entrez Gene: 55994 Mouse

Entrez Gene: 85435 Rat

Omim: 603295 Human

SwissProt: O15198 Human

SwissProt: Q9JIW5 Mouse

SwissProt: O54835 Rat

Unigene: 123119 Human

Unigene: 244353 Mouse

Unigene: 10862 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 www.www.p2b3.cn 北京博奧森生物技術(shù)有限公司
通過(guò)國(guó)際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書(shū)編號(hào): 00124Q34771R2M/1100
通過(guò)國(guó)際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書(shū)編號(hào): CQC24QY10047R0M/1100
京ICP備05066980號(hào)-1         京公網(wǎng)安備110107000727號(hào)
牡丹江市| 公主岭市| 墨竹工卡县| 东明县| 金寨县| 崇仁县| 留坝县| 汾阳市| 满洲里市| 凯里市| 绥中县| 阿鲁科尔沁旗| 衡阳县| 和林格尔县| 大悟县| 从化市| 慈溪市| 郎溪县| 怀集县| 阿拉善左旗| 惠安县| 静乐县| 岐山县| 富源县| 奈曼旗| 大埔区| 罗江县| 大姚县| 双牌县| 洞口县| 犍为县| 遂宁市| 敦煌市| 潼南县| 永嘉县| 白银市| 比如县| 沾化县| 张家界市| 怀安县| 伊通|