| 產(chǎn)品編號 | bs-12340R-BF488 |
| 英文名稱 | Rabbit Anti-VNN2/BF488 Conjugated antibody |
| 中文名稱 | BF488標(biāo)記的血管非炎性蛋白2抗體 |
| 別 名 | FOAP 4; FOAP-4; Glycosylphosphatidyl inositol-anchored protein GPI-80; GPI 80; GPI-80; OTTHUMP00000017228; OTTHUMP00000233789; OTTHUMP00000233791; pantetheinase; Protein FOAP-4; vanin 2; Vanin-2; Vannin 2; Vascular non-inflammatory molecule 2; VNN2_HUMAN. |
| 規(guī)格價格 | 100ul/2980元 購買 大包裝/詢價 |
| 說 明 書 | 100ul |
| 研究領(lǐng)域 | 腫瘤 心血管 發(fā)育生物學(xué) 干細胞 細胞粘附分子 新陳代謝 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Sheep, ) |
| 產(chǎn)品應(yīng)用 | ICC=1:50-200 IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 59kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from Human VNN2 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol |
| 保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
background: Vanin-2 is a 520 amino acid GPI-anchor protein that belongs to the CN hydrolase family and BTD/VNN subfamily.Widely expressed with high expression in spleen and blood, vanin-2 is suggested to be involved in thymus homing of bone marrow cells, regulation of Integrin ∫2-mediated cell adhesion, and migration and motility of neutrophils. Vanin-2 exists as five alternatively spliced isoforms and is encoded by a gene mapping to human chromosome 6q23.2. Function: This gene product is a member of the Vanin family of proteins which share extensive sequence similarity with each other, and also with biotinidase. The family includes secreted and membrane-associated proteins, a few of which have been reported to participate in hematopoietic cell trafficking. No biotinidase activity has been demonstrated for any of the vanin proteins, however, they possess pantetheinase activity, which may play a role in oxidative-stress response. The encoded protein is a GPI-anchored cell surface molecule that plays a role in transendothelial migration of neutrophils. This gene lies in close proximity to, and in same transcriptional orientation as two other vanin genes on chromosome 6q23-q24. Two transcript variants encoding different isoforms have been described for this gene. Subcellular Location: Cell Membrane; Lipid-anchor, GPI-anchor Tissue Specificity: Widely expressed with higher expression in spleen and blood. Similarity: Belongs to the CN hydrolase family. BTD/VNN subfamily. Contains 1 CN hydrolase domain. Database links: UniProtKB/Swiss-Prot: O95498.3 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
