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Rabbit Anti-ZBED4/Gold Conjugated antibody (bs-13554R-Gold)
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說 明 書: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號 bs-13554R-Gold
英文名稱 Rabbit Anti-ZBED4/Gold Conjugated antibody
中文名稱 膠體金標(biāo)記的鋅指蛋白BED4抗體
別    名 Zinc finger BED domain containing 4; Zinc finger BED domain containing protein 4; Zinc finger BED type containing 4; ZBED4_HUMAN.  
規(guī)格價(jià)格 100ul/2980元 購買        大包裝/詢價(jià)
說 明 書 100ul(10nm  15nm  35nm
研究領(lǐng)域 細(xì)胞生物  信號轉(zhuǎn)導(dǎo)  鋅指蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Pig, Horse, )
產(chǎn)品應(yīng)用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 130kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human ZBED4
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產(chǎn)品介紹 background:
The zinc finger BED domain-containing protein family (ZBED) is comprised of ZBED1, ZBED2, ZBED3, ZBED4 and ZBED5. They each contain one BED-type zinc finger domains with the exception of ZBED4, which contain 4 BED-type zinc finger domains. ZBED1 is thought to function as a transcription factor that regulates a number of ribosomal protein (RP) encoded genes by binding specifically to 5'-TGTCG[CT]GA[CT]A-3' DNA regions found in RP promotors. ZBED3 is an Axin-binding protein involved in Wnt/beta-catenin signaling modulation. ZBED4 expression has been shown in human and mouse retinas where it is thought to act as a regulatory protein in cone photoreceptors and Müller cells. The functions of ZBED2 and ZBED5 have yet to be elucidated.

Subunit:
Homodimer.

Subcellular Location:
Cytoplasmic and Nuclear

Tissue Specificity:
Widely expressed with highest levels in testis, kidney and spinal cord and brain corpus callosum. Expressed in the retina, found in the cone photoreceptors, Mueller cells, cone pedicles and in the innermost retinal layer.

Similarity:
Contains 4 BED-type zinc fingers.

Database links:

Entrez Gene: 9889 Human

Omim: 612552 Human

SwissProt: O75132 Human

Unigene: 475208 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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