mm1313亚洲精品,欧美俄罗斯40老熟妇,欧美日韩在线观看视频在线,亚洲欧美国产激情综合在线

掃碼關(guān)注公眾號(hào)           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  人才招聘  關(guān)于我們  聯(lián)系我們
牛牛视频一区二区三区,精品国产av一区二区,中文字幕亚洲欧美精品
Rabbit Anti-C2a/BF488 Conjugated antibody (bs-10428R-BF488)
訂購(gòu)熱線:400-901-9800
訂購(gòu)郵箱:sales@www.p2b3.cn
訂購(gòu)QQ:  400-901-9800
技術(shù)支持:techsupport@www.p2b3.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-10428R-BF488
英文名稱1 Rabbit Anti-C2a/BF488 Conjugated antibody
中文名稱 BF488標(biāo)記的補(bǔ)體C2a鏈多肽抗體
別    名 Complement C2a fragment; C2; C2 protein; C3/C5 convertase; CO 2; CO2; complement C2; Complement component 2; complement component C2; DKFZp779M0311; OTTHUMP00000062690; CO2_HUMAN.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買        大包裝/詢價(jià)
說 明 書 100ul  
研究領(lǐng)域 心血管  免疫學(xué)  糖蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, )
產(chǎn)品應(yīng)用
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 56kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human C2a
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
Component C2 is a serum glycoprotein that functions as part of the classical pathway of the complement system. Activated C1 cleaves C2 into C2a and C2b. The serine proteinase C2a then combines with complement factor 4b to create the C3 or C5 convertase. Deficiency of C2 has been reported to associated with certain autoimmune diseases and SNPs in this gene have been associated with altered susceptibility to age-related macular degeneration. This gene localizes within the class III region of the MHC on the short arm of chromosome 6. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described in publications but their full-length sequence has not been determined.[provided by RefSeq, Mar 2009].

Function:
Component C2 which is part of the classical pathway ofthe complement system is cleaved by activated factor C1 into twofragments: C2b and C2a. C2a, a serine protease, then combines withcomplement factor 4b to generate the C3 or C5 convertase.

Subunit:
C2a interacts with Schistosoma haematobium TOR (viaN-terminal extracellular domain). This results in inhibition of theclassical and lectin pathway of complement activation, probably dueto interference with binding of C2a to C4b such that C3 convertasecannot be formed. This infers resistance to complement-mediatedcell lysis, allowing parasite survival and infection.

Subcellular Location:
Secreted.

DISEASE:
Defects in C2 are the cause of complement component 2deficiency (C2D) [MIM:217000]. A deficiency of the complementclassical pathway associated with the development of autoimmunedisorders, mainly systemic lupus erythematosus. Skin and jointmanifestations are common and renal disease is relatively rare.Patients with complement component 2 deficiency are also reportedto have recurrent or invasive infections.

Similarity:
Belongs to the peptidase S1 family.
Contains 1 peptidase S1 domain.
Contains 3 Sushi (CCP/SCR) domains.
Contains 1 VWFA domain.

Database links:

Entrez Gene: 717 Human

Omim: 217000 Human

SwissProt: P06681 Human

Unigene: 408903 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 www.www.p2b3.cn 北京博奧森生物技術(shù)有限公司
通過國(guó)際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號(hào): 00124Q34771R2M/1100
通過國(guó)際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號(hào): CQC24QY10047R0M/1100
京ICP備05066980號(hào)-1         京公網(wǎng)安備110107000727號(hào)
精河县| 荆州市| 桃江县| 连江县| 武城县| 芜湖市| 盐边县| 府谷县| 盐源县| 商丘市| 泾川县| 化隆| 马龙县| 洛宁县| 杭锦后旗| 高陵县| 曲靖市| 渭源县| 寿阳县| 鄂托克前旗| 紫阳县| 陆川县| 高要市| 杨浦区| 凌海市| 昭平县| 石嘴山市| 温宿县| 揭东县| 祁门县| 应用必备| 伽师县| 太仆寺旗| 余庆县| 新宁县| 余庆县| 婺源县| 禹州市| 和林格尔县| 蓬莱市| 元谋县|