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Rabbit Anti-TP53INP2/PE-Cy5.5 Conjugated antibody (bs-17160R-PE-Cy5.5)
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說(shuō) 明 書(shū): 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-17160R-PE-Cy5.5
英文名稱1 Rabbit Anti-TP53INP2/PE-Cy5.5 Conjugated antibody
中文名稱 PE-Cy5.5標(biāo)記的腫瘤蛋白p53誘導(dǎo)核內(nèi)蛋白2抗體
別    名 C20orf110; Diabetes and obesity regulated; p53 inducible protein U; DOR; p53-inducible protein U; PIG-U; PINH; T53I2_HUMAN; Tp53inp2; Tumor protein p53-inducible nuclear protein 2.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買        大包裝/詢價(jià)
說(shuō) 明 書(shū) 100ul  
研究領(lǐng)域 腫瘤  細(xì)胞生物  染色質(zhì)和核信號(hào)  腫瘤細(xì)胞生物標(biāo)志物  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Mouse, Rat,  (predicted: Human, )
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 24kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human TP53INP2
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 Function:
Dual regulator of transcription and autophagy. Positively regulates autophagy and is required for autophagosome formation and processing. May act as a scaffold protein that recruits MAP1LC3A, GABARAP and GABARAPL2 and brings them to the autophagosome membrane by interacting with VMP1 where, in cooperation with the BECN1-PI3-kinase class III complex, they trigger autophagosome development. Acts as a transcriptional activator of THRA.

Subunit:
Interacts with VMP1, GABARAP, GABARAPL1, GABARAPL2, MAP1LC3A, MAP1LC3B, MAP1LC3C and THRA.

Subcellular Location:
Nucleus.

Database links:

Entrez Gene: 58476 Human

Entrez Gene: 68728 Mouse

Entrez Gene: 362246 Rat

SwissProt: Q8IXH6 Human

SwissProt: Q8CFU8 Mouse

SwissProt: Q8CHM3 Rat

Unigene: 516994 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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