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Rabbit Anti-Josephin-1/Gold Conjugated antibody (bs-17206R-Gold)
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說 明 書: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-17206R-Gold
英文名稱1 Rabbit Anti-Josephin-1/Gold Conjugated antibody
中文名稱 膠體金標記的JOSD1蛋白抗體
別    名 dJ508I15.2; JOS1_HUMAN; Josd1; Josephin 1; Josephin domain containing 1; Josephin domain-containing 1; Josephin-1; KIAA0063; OTTHUMP00000198984; OTTHUMP00000239365.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul(10nm  15nm  35nm
研究領(lǐng)域 細胞生物  發(fā)育生物學(xué)  泛素  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human,  (predicted: Mouse, Rat, Chicken, Dog, Pig, Horse, Cat, )
產(chǎn)品應(yīng)用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 23kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human JOSD1
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產(chǎn)品介紹 background:
Josephin-1 is a 202 amino acid protein that contains one josephin domain and is encoded by a gene that maps to human chromosome 22. Chromosome 22 houses over 500 genes and is the second smallest human chromosome. Mutations in several of the genes that map to chromosome 22 are involved in the development of Phelan-McDermid syndrome, Neurofibromatosis type 2, autism and schizophrenia. Additionally, translocations between chromosomes 9 and 22 may lead to the formation of the Philadelphia Chromosome and the subsequent production of the novel fusion protein BCR-Abl, a potent cell proliferation activator found in several types of leukemias.

Function:
Has low protease activity towards poly-ubiquitin chains (in vitro). May act as a deubiquitinating enzyme.

Subunit:
Interacts with beta-actin/ACTB.

Similarity:
Contains 1 Josephin domain.

Database links:

Entrez Gene: 9929 Human

Entrez Gene: 74158 Mouse

Entrez Gene: 315134 Rat

SwissProt: Q15040 Human

SwissProt: Q9DBJ6 Mouse

SwissProt: Q5BJY4 Rat

Unigene: 3094 Human

Unigene: 2495 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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