| 產(chǎn)品編號(hào) | bs-17033R-BF488 |
| 英文名稱1 | Rabbit Anti-KIAA2022/BF488 Conjugated antibody |
| 中文名稱 | BF488標(biāo)記的KIAA2022蛋白抗體 |
| 別 名 | Protein KIAA2022; expressed sequence C77370; K2022_HUMAN; Kiaa2022; RP11-130N24.1; RP23-35L3.1; Uncharacterized protein KIAA2022. |
| 規(guī)格價(jià)格 | 100ul/2980元 購(gòu)買 大包裝/詢價(jià) |
| 說 明 書 | 100ul |
| 研究領(lǐng)域 | 腫瘤 細(xì)胞生物 免疫學(xué) 發(fā)育生物學(xué) 表觀遺傳學(xué) |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human, Mouse, Rat, Pig, Horse, ) |
| 產(chǎn)品應(yīng)用 | ICC=1:50-200 IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 167kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human Protein KIAA2022 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲(chǔ) 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol |
| 保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
background: KIAA2022 is a 1,516 amino acid protein that is highly expressed in both adult and fetal brain and is encoded by a gene which maps to human chromosome X. Chromosomal aberrations involving the KIAA2022 gene are associate with the development of severe mental retardation, suggesting a role for KIAA2022 in normal brain development and function. Human chromosome X, on which the KIAA2022 gene is localized, contains nearly 153 million base pairs and houses over 1,000 genes. In conjunction with chromosome Y, chromosome X is responsible for sex determination. There are a number of conditions related to an abnormal number and combination of sex chromosomes, some of which include Turner's syndrome, color blindness, hemophilia and Duchenne muscular dystrophy. Tissue Specificity: Highly expressed in fetal and adult brain, predominantly in the cerebral cortex and the cerebellum. Also expressed in other tissues but to a lesser extent. DISEASE: Note=A chromosomal aberration involving KIAA2022 is found in 2 patients with severe mental retardation (MR). Pericentric inversion inv(X)(p22.3;q13.2). The Xq13 breakpoint lies within a predicted intron of KIAA2022 gene. KIAA2022 protein is no longer expressed in these patients lymphocytes. Database links: Entrez Gene: 340533 Human Omim: 300524 Human SwissProt: Q5QGS0 Human Entrez Gene: 100173017 Orangutan Entrez Gene: 716288 Rhesus monkey Omim: 607359 Human SwissProt: Q8N163 Human SwissProt: Q8VDP4 Mouse SwissProt: Q5R8S0 Orangutan Unigene: 433722 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
