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Rabbit Anti-C Peptide/BF488 Conjugated antibody (bs-23205R-BF488)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-23205R-BF488
英文名稱1 Rabbit Anti-C Peptide/BF488 Conjugated antibody
中文名稱 BF488標記的小鼠C-肽抗體
別    名 proinsulin precursor; Hyperproinsulinemia; INS; Insulin Precursor; IRDN; Proinsulin; Propeptide; C-Peptide; INS2_MOUSE.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 腫瘤  細胞生物  信號轉導  生長因子和激素  糖尿病  細胞因子  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Mouse, Rat, )
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 3kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from mouse C Peptide
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
C Peptide is part of the molecule of Proinsulin, that consists of three parts: C Peptide and two long strands of amino acids (called the alpha and beta chains) that later become linked together to form the insulin molecule. From every molecule of proinsulin, one molecule of insulin plus one molecule of C Peptide are produced. C peptide is released into the blood stream in equal amounts to insulin. A test of C peptide levels will show how much insulin the body is making. Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.

Function:
Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.

Subunit:
Heterodimer of a B chain and an A chain linked by two disulfide bonds.

Subcellular Location:
Secreted.

Similarity:
Belongs to the insulin family.

Database links:

Entrez Gene: 3630 Human

Entrez Gene: 16334 Mouse

Omim: 176730 Human

SwissProt: P01308 Human

SwissProt: P01326 Mouse

Unigene: 272259 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

C肽是胰島β細胞的分泌產物,與大、小鼠有部分交叉,它與胰島素有一個共同的前體——胰島素原
C肽是連接肽,因為最初它是連接A、B兩條鏈的中間段,胰島素原分解后才能獨立存在,它也能從細胞釋放到血液中。因此,從胰島細胞分泌入血的主要成分有兩種,一種是人們所熟悉的胰島素,另一種就是C肽。
近年來,隨著深入的研究,發(fā)現C肽是具有生物學活性的。并且,這種生物學活性對于延緩糖尿病慢性并發(fā)癥的發(fā)生和發(fā)展可能具有重要的作用.
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