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Rabbit Anti-CD200 /AP Conjugated antibody (bs-23468R-AP)
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說(shuō) 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-23468R-AP
英文名稱1 Rabbit Anti-CD200 /AP Conjugated antibody
中文名稱 堿性磷酸酶(AP)標(biāo)記的膜糖蛋白CD200抗體
別    名 CD200; CD200 antigen; CD200 molecule; MOX1; MOX2; MRC; MRC OX 2 antigen; My033; OX 2; OX 2 membrane glycoprotein precursor; OX-2 membrane glycoprotein; OX2G; OX2G_HUMAN.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買        大包裝/詢價(jià)
說(shuō) 明 書 100ul  
研究領(lǐng)域 細(xì)胞生物  免疫學(xué)  細(xì)胞表面分子  糖蛋白  淋巴細(xì)胞  t-淋巴細(xì)胞  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human,  (predicted: Mouse, )
產(chǎn)品應(yīng)用 WB=1:50-200 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 28kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human CD200
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 Constituents: 0.05M TBS, pH 8.0 with 10mg/ml BSA and 0.05% NaN3, 50% glycerol. Or Lyophilized. Buffer = 0.05M TBS, pH 8.0 with 10mg/ml BSA and 0.05% NaN3. Reconstitute with sterile distilled water.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 Function:
Costimulates T-cell proliferation. May regulate myeloid cell activity in a variety of tissues.

Subunit:
Interacts with CD200R1.

Subcellular Location:
Cell membrane; Single-pass type I membrane protein.

Similarity:
Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
Contains 1 Ig-like V-type (immunoglobulin-like) domain.

Database links:

Entrez Gene: 4345 Human

Omim: 155970 Human

SwissProt: P41217 Human

Unigene: 79015 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

CD200是Ⅰ型膜糖蛋白,為免疫球蛋白超家族的新成員,廣泛表達(dá)在人類胸腺細(xì)胞、B細(xì)胞、激活的T細(xì)胞、濾泡狀樹突細(xì)胞、神經(jīng)元及血管內(nèi)皮上??杀磉_(dá)于B細(xì)胞及其增殖性疾病和一部分T細(xì)胞。近年來(lái)研究發(fā)現(xiàn),CD200與CD200R間的相互作用可以傳遞抑制性信號(hào)減低髓樣細(xì)胞的活性,改變其遷移。CD200在免疫疾病和抑制排斥反應(yīng)中作為一種免疫耐受信號(hào),它的一些相關(guān)分子在免疫調(diào)節(jié)中也具有一定的作用。
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